二陈平胃散和三子养亲汤加减治疗痰湿蕴肺型咳嗽疗效观察

Clinical Observation on Modified Erchen Pingwei Powder and Sanzi Yangqin Tang in the Treatment of Phlegm-dampness Accumulation in Lung Pattern Cough

目的:观察二陈平胃散和三子养亲汤加减治疗痰湿蕴肺型咳嗽的临床疗效。方法:将痰湿蕴肺型咳嗽患者90例随机分为对照组(西药治疗)和试验组(加用二陈平胃散和三子养亲汤加减)各45例。观察两组患者肺机能恢复情况、呼吸困难程度、咳嗽症状、视觉模拟量表(visual analog scale,VAS)评分、生活质量及唾液分泌型免疫球蛋白A(secreted immunoglobulin A,SIgA)水平。结果:治疗后试验组、对照组显效率分别为82.2%、60.0%,差异有统计学意义(P<0.05)。两组患者治疗后呼吸困难程度、生存质量、VAS评分、咳嗽症状评分与治疗前比较差异有统计学意义(P<0.05),试验组低于对照组(P<0.05)。治疗后两组患者唾液sIgA水平与治疗前比较差异有统计学意义(P<0.05),试验组高于对照组(P<0.05)。结论:二陈平胃散和三子养亲汤加减联合西药能改善痰湿蕴肺型咳嗽患者临床症状、呼吸困难、生存质量及免疫功能,效果优于单纯西药治疗。

Objective:To observe clinical effects of modified Erchen Pingwei powder and Sanzi Yangqin Tang in the treatment of phlegm-dampness accumulation in lung pattern cough.Methods:All 90 patients were randomized into the control group(Western medicine treatment)and the experiment group(modified Erchen Pingwei powder and Sanzi Yangqin Tang),with 45 cases in each group.To observe the recovery function of pulmonary function,the degree of dyspnea,cough symptoms,VAS scores,quality of life and the levels of sIgA in saliva.Results:After the treatment,markedly effective rates of the experiment group and the control group were 82.2%and 60.0%respectively,and the difference had statistical meaning(P<0.05).The difference was statistically significant when the degrees of dyspnea,survival quality,VAS scores,cough symptoms scores after the treatment in both groups were compared with these before the treatment(P<0.05),the experiment group was lower than the control group(P<0.05).There was a significant difference when the levels of saliva in both groups after the treatment were compared with these before the treatment(P<0.05),the experiment group was higher than the control group(P<0.05).Conclusion:Modified Erchen Pingwei powder and Sanzi Yangqin Tang in the treatment of phlegm-dampness accumulation in lung pattern cough could improve clinical symptoms,dyspnea,survival quality and immune function,and its effects are superior to these of Western medicine therapy.