体重变化与乳腺癌放疗位置精度的相关性研究

Correlation between body weight change and position accuracy of breast cancer radiotherapy

目的探讨体重变化在乳腺癌根治术后放疗中位置精度的相关性。方法选取2020年5月至2022年3月华中科技大学同济医学院附属同济医院接受放疗的167例乳腺癌改良根治术后患者为研究对象,通过对患者前3次及后每周行锥形束CT影像验证,记录患者体重,共获取1076组数据,按BMI和体重增减幅度区间分别分析。结果超重和肥胖患者的体重增重与减重幅度值比较,差异有统计学意义(P<0.05)。各体重增减在X、Y轴线性平移方向误差值比较,差异有统计学意义(P<0.05)。在X、Y轴线性平移方向不同BMI患者中,超重患者及肥胖患者各体重增减在X轴线性平移方向误差比较,差异有统计学意义(P<0.05),未超重患者各体重增减在Y轴线性平移方向误差比较,差异有统计学意义(P<0.05)。结论乳腺癌根治术后患者的体重变化会影响放疗位置精度。

Objective To explore the correlation of body weight change with positional accuracy in radiotherapy after radical mastectomy.Methods From May 2020 to March 2022,a total of 167 patients with modified radical mastectomy in Tongji hospital,Tongji Medical College of Huazhong University of Science and Technology,were taken as the research object.The cone beam CT images of patients were verified three times before and every week after,and the patient’s weight was recorded.A total of 1076 group of data were obtained.The data were grouped and analyzed according to BMI and the range of weight increase and decrease.Results There was a significant difference between overweight and obese patients in weight gain and weight loss(P<0.05).There was a significant difference between the error values of weight gain and loss in X and Y axes translational direction(P<0.05).there was a statistical difference between overweight patients and obese patients in X-axis translational direction error(P<0.05),and there was a statistical difference between overweight patients and obese patients in Y-axis translational direction error(P<0.05).Conclusion The weight change of patients after radical mastectomy will affect the position accuracy of radiotherapy.