干燥综合征与肠道微生态相关性研究进展

Research progress on the relationship between Sjogren’s syndrome and intestinal microecology

干燥综合征(Sjogren’s syndrome,SS)是以眼干和口干为主要临床症状的自身免疫性疾病,SS患者在疾病后期存在一些难以忍受且不可逆的症状,因此探索SS的发病机制及其与肠道微生态之间的关系至关重要。本文旨在讨论SS与肠道微生态之间的相互作用机制,从而对患者肠道菌群的组成,多样性进行深入了解;同时总结关于干燥综合征的一些新治疗手段。

Sjogren’s syndrome(SS)is an autoimmune disease with dry eyes and dry mouth as the main clinical symptoms.There are some intolerable and irreversible symptoms in the later stage of the patients with disease SS.Thus,it is crucial to explore the pathogenesis of SS and its relationship with intestinal microecology.This paper aimed to discuss the interaction mechanism between SS and intestinal microecology,so as to have a deep understanding of the composition and diversity of intestinal microbiota in SS patients.At the same time,some new treatments for Sjogren’s syndrome were summarized.