双嘧达莫杂质定位溶液的制备和应用

Method of Preparing and Applying Identification Solution of Dipyridamole Impurities

目的:提供双嘧达莫杂质定位溶液的制备方法以及应用示例。方法:采用化学合成的方式合成出双嘧达莫杂质定位溶液,参照《英国药典》2022年版色谱条件进行应用展示。结果:该定位溶液能准确定位双嘧达莫杂质A、杂质B、杂质C和杂质D。结论:该方法制备定位溶液制作简单,使用简便,准确度高,能在一定程度上起到代替对照品的作用。

Objective:Provide a preparation method and application example of identification solution of Dipyridamole impurities. Methods:Identification solution of Dipyridamole impurities was synthesized by chemical synthesis and showed by BP2022 conditions for application demonstration. Results: The solution can accurately identify specified impurities A,B,C and D of Dipyridamole. Conclusion: The identification solution is prepared simply, convenient and highly accurate. It can replace the reference substance to a certain extent.