鼻内镜下等离子低温射频消融术治疗儿童OSAHS的临床疗效

Clinical Efficacy of Nasal Endoscopic Plasma Cryogenic Radiofrequency Ablation in the Treatment of OSAHS in Children

目的:探讨鼻内镜下等离子低温射频消融术治疗儿童阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的临床疗效。方法:选取2017年6月-2022年6月南京医科大学附属江宁医院耳鼻咽喉科收治的OSAHS患儿108例为研究对象,根据随机数字表法分为对照组和观察组,各54例。对照组给予常规手术治疗,观察组给予鼻内镜下等离子低温射频消融术治疗。比较两组患儿临床疗效、疼痛程度[视觉模拟评分法(VAS)]、手术前后的通气指标[呼吸暂停低通气指数(AHI)、氧减指数(ODI)、最低血氧饱和度(LOSaO_(2))及平均血氧饱和度(MnSaO_(2))]。结果:两组患儿治疗总有效率比较,差异无统计学意义(P>0.05);术后24、48、72 h,观察组疼痛感低于对照组,差异有统计学意义(P<0.05);术后1、3个月,两组患者AHI及ODI水平均降低,LOSaO_(2)及MnSaO_(2)水平均升高,观察组AHI及ODI水平低于对照组,LOSaO_(2)及MnSaO_(2)水平高于对照组,差异有统计学意义(P<0.05)。结论:鼻内镜下等离子低温射频消融术治疗儿童OSAHS的临床疗效较好,可有效改善患儿通气指标,缓解患儿疼痛程度。

Objective:To investigate the clinical efficacy of nasal endoscopic plasma cryogenic radiofrequency ablation in the Treatment of OSAHS in Children for the treatment of obstructive sleep apnea hypopnea syndrome(OSAHS).Methods:One hundred and eight children with OSAHS admitted to the Department of Otolaryngology,Jiangning Hospital Affiliated to Nanjing Medical University,from June 2017 to June 2022 were selected as the study subjects,and were divided into control and observation groups according to the random number table method,with 54 cases each.The control group was given conventional surgical treatment,and the observation group was given nasal endoscopic plasma cryogenic radiofrequency ablation treatment.The clinical efficacy,pain level[visual analog scoring method(VAS)],ventilation indexes[apnea hypoventilation index(AHI),oxygen desaturation index(ODI),minimum oxygen saturation(LOSaO_(2))and mean oxygen saturation(MnSaO_(2))]before and after the surgery were compared between the two groups.Results:There was no statistically significant difference in the total efficiency of treatment between the two groups of children(P>0.05).At 24,48 and 72 h postoperatively,the pain in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).At 1 and 3 months after surgery,the AHI and ODI levels decreased,and the LOSaO_(2) and MnSaO_(2) levels increased in both groups.The AHI and ODI levels in the observation group were lower than those in the control group,and the LOSaO_(2) and MnSaO_(2) levels were higher than those in the control group,with statistically significant differences(P<0.05).Conclusion:The clinical efficacy of nasal endoscopic plasma cryogenic radiofrequency ablation for the treatment of OSAHS in children is better,which can effectively improve the ventilation index and relieve the pain level of the children.