二氧化碳点阵激光联合丙酸氟替卡松乳膏治疗稳定期白癜风的临床价值

Clinical Value of CO_(2) Dot Array Laser Combined with Fluticasone Propionate Cream in Treatment of Stable Vitiligo

目的:探讨二氧化碳(CO_(2))点阵激光联合丙酸氟替卡松乳膏治疗稳定期白癜风的临床价值。方法:选取2019年6月-2021年6月山东省微山县人民医院皮肤科收治的86例稳定期白癜风患者为研究对象,根据治疗方案的不同分为观察组和对照组,各43例。对照组口服复方木尼孜其颗粒联合外用丙酸氟替卡松软膏治疗,观察组采用CO_(2)点阵激光联合丙酸氟替卡松乳膏药物治疗。比较两组治疗3个月后治疗效果及治疗期间不良反应发生情况。结果:治疗3个月后,观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。观察组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论:在稳定期白癜风患者的治疗中,应用CO_(2)点阵激光联合丙酸氟替卡松乳膏可以显著提高治疗效果,减少患者治疗期间不良反应的发生。

Objective:To investigate the clinical value of carbon dioxide(CO_(2)) dot array laser combined with fluticasone propionate cream in the treatment of stable vitiligo.Methods:From June 2019 to June 2021,a total of 86 patients with stable vitiligo admitted to Department of Dermatology,Weishan People’s Hospital in Shandong Province were selected as the study subjects.They were divided into observation group and control group according to the different treatment regimens,with 43 cases in each group.The control group was treated with oral administration of Compound Muniziqi Granules combined with external application of fluticasone propionate cream,and observation group was treated with CO_(2) dot array laser combined with fluticasone propionate cream.The curative effect after 3 months of treatment and the incidence of adverse reactions during treatment were compared between the two groups.Results:After three months of treatment,the total effective rate in the observation group was higher than that in the control group,with a statistically significant difference(P<0.05).The incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:In the treatment of patients with stable vitiligo,CO_(2)dot array laser combined with fluticasone propionate cream can significantly improve the curative effect and reduce the occurrence of adverse reactions during treatment.