卒中后抑郁预测量表的汉化及筛查价值研究

Study on the Chinese version and screening value of post-stroke depression prediction scale

目的翻译卒中后抑郁预测量表(post-stroke depression prediction scale,DePreS),并探讨其对卒中后抑郁的早期预测效果。方法采用翻译、回译和文化调适,确定中文版卒中后抑郁预测量表的条目,检验量表的效度。采用便利抽样法,选取123例卒中患者作为研究对象,在患者卒中后第1周对其使用中文版卒中后抑郁预测量表进行评分,在卒中后第7~9周以中国精神障碍分类与诊断标准第3版为金标准,获取中文版卒中后抑郁预测量表的临界值,并判断其对卒中后抑郁的早期筛查价值。结果中文版卒中后抑郁预测量表内容效度指数为0.958,各条目得分与总分的相关系数为0.423~0.526(均P<0.001),临界比值为4.870~7.732(均P<0.001),鉴别效度较高(Z=37.497,P<0.001)。该量表预测卒中后抑郁的临界值为2分,其灵敏度为71.74%,特异度为80.52%,受试者工作特征曲线下面积为0.831(95%CI:0.753~0.892)。结论中文版卒中后抑郁预测量表对卒中后抑郁的预测准确性较高,可用于卒中患者抑郁的早期筛查。

Objective The post-stroke depression prediction scale(DePreS)was translated and Chinese localized to explore its predictive effect on post-stroke depression(PSD).Methods After translation,back-translation and cultural adjustment,the final Chinese version of DePreS was settled,the validity of Chinese version was tested.Then a total of 123 stroke survivors were selected using the convenience sampling method,and surveyed using the Chinese version in the 1st week after the stroke.At the 7 to 9 weeks after stroke,Chinese classification and diagnostic criteria of mental disorders-3(CCMD-3)was employed to evaluate the patients to obtain the critical value of post-stroke depression for the Chinese version of DePreS.Results The content validity index of the scale was 0.958 and the correlation coefficient between each item score and the total score was 0.423~0.526(P<0.001 for all).Moreover,the CR value was 4.870~7.732(P<0.001 for all),with high discriminant validity(Z=37.497,P<0.001),the optimal critical value of PSD was 2,and the sensitivity and specificity of the Chinese version were 71.74%and 80.52%respectively.The area under the curve was 0.831(95%CI:0.753~0.892).Conclusion The Chinese version of DePreS has high accuracy in predicting PSD,which can be used for the early screening of PSD among stroke survivors.