经皮椎体成形术治疗骨质疏松性椎体压缩性骨折疗效分析

Therapeutic Effect of Percutaneous Vertebroplasty in the Treatment of Osteoporotic Vertebral Compression Fracture

目的探究经皮椎体成形术(PVP)治疗骨质疏松性椎体压缩性骨折(OVCF)的临床疗效。方法选取2019年12月至2020年11月泰兴市中医院收治的154例OVCF患者作为研究对象,并按照随机数表法将其随机分为观察组(77例)与对照组(77例),观察组患者采用PVP治疗,对照组患者采用过伸复位治疗,对比观察两组患者疼痛程度、椎体功能、伤椎前缘高度、Cobb角以及并发症发生情况结果术后1周及术后1、5个月,观察组患者视觉模拟评分法(VAS)评分及Oswestry功能障碍指数(ODI)评分均明显低于对照组(VAS:t=1.985、2.733、2.490,P=0.049、0.007、0.014;ODI:t=2.726、8.181、8.497,P=0.007、P<0.001、P<0.001);术后1个月,观察组患者伤椎前缘高度明显高于对照组(t=6.786,P<0.001),Cobb角明显小于对照组(t=20.927,P<0.001);观察组患者术后并发症发生率为5.19%,明显低于对照组患者的术后并发症发生率15.58%(χ^(2)=4.464,P=0.035)。结论PVP可明显缓解OVCF患者疼痛程度,改善患者椎体功能,且安全性较高。

Objective To study the therapeutic effect of percutaneous vertebroplasty(PVP)in the treatment of osteoporotic vertebral compression fracture(OVCF).Methods 154 patients with OVCF,admitted to Taixing Hospital of TCM from December 2019 to November 2020,were enrolled as research subjects and then divided,using the random number table,into observation group(n=77)and control group(n=77).Patients in observation group were treated with PVP,whereas the patients in control group were treated with hyperextension reduction.The pain degree,vertebral function,anterior edge height and Cobb angle of injured vertebra,and occurrence of complications were compared between the two groups.Results The scores of visual analogue scale(VAS)and Oswestry disability index(ODI)of patients were significantly lower in observation group compared with control group respectively on one week,one month and five months after operation(VAS:t=1.985,2.733 and 2.490,P=0.049,0.007 and 0.014;ODI:t=2.726,8.181 and 8.497,P=0.007,P<0.001,P<0.001);one month after operation,in observation group,the height of the anterior edge of the injured vertebra was significantly higher(t=6.786,P<0.001),and the Cobb angle was significantly smaller(t=20.927,P<0.001),compared with control group;the incidence of postoperative complications was 5.19%in observation group,significantly lower than 15.58%in control group(χ^(2)=4.464,P=0.035).Conclusion PVP can significantly alleviate the pain of patients with OVCF,improve their vertebral function,and is also very safe to use.