原发性肾上腺淋巴瘤并颅内侵犯的临诊应对

Management of primary adrenal lymphoma with intracranial invasion

原发性肾上腺淋巴瘤(primary adrenal lymphoma,PAL)是一种罕见的结节外淋巴瘤。因其临床和影像学特点不典型,误诊率极高,确诊依靠组织病理学检查。患者常因影像学检查发现肾上腺意外瘤而在内分泌科就诊。PAL常伴有其他组织和器官侵犯,死亡率较高,预后较差。本文对1例原发性肾上腺淋巴瘤并颅内侵犯患者的临床特点进行分析,并对该病的发病机制、临床表现、诊断及治疗等进行文献复习。

Primary adrenal lymphoma(PAL)is a rare extranodular lymphoma.It is subject to misdiagnosis due to atypical clinical and imaging features.Histopathology is required to establish the diagnosis.Patients often present to the Endocrinology Department upon revelation of adrenal incidentalomas by imaging.PAL is often accompanied by invasion of other tissues and organs,with a high mortality rate and a poor prognosis.In this paper,the clinical features of a patient with primary adrenal lymphoma and intracranial invasion were summarized,and the pathogenesis,clinical manifestations,diagnosis and treatment of this disease were reviewed.