铁路职工血尿酸水平与高尿酸血症流行特征分析

Analysis of Serum Uric Acid Level and Epidemic Characteristics of Hyperuricemia among Railway Workers

了解铁路职工血尿酸(SUA)水平及高尿酸血症(HUA)流行特征,为高尿酸血症的防治提供依据。收集2021年某地区参加健康体检的31 415名铁路职工的体检资料,对SUA、HUA流行特征进行统计分析,计数资料的比较采用χ^(2)检验,计量资料两组间的比较采用t检验。结果表明,该地区铁路职工血尿酸水平为(377.00±91.94)μmol/L,男性(391.31±86.17)μmol/L,女性(290.1±76.81)μmol/L;调查人群中HUA总患病率为31.43%,男性HUA患病率33.78%,高于女性患病率(17.17%),差异有统计学意义(χ^(2)=487.531,P<0.01);不同年龄组间HUA患病率差异有统计学意义(χ^(2)=405.398,P<0.05),患病率随年龄增长呈下降趋势(趋势χ^(2)=397.239,P<0.01),其中男性HUA患病率年龄组差异有统计学意义且随年龄增长呈下降趋势;不同系统间HUA患病率差异有统计学意义(χ^(2)=243.716,P<0.01),机务、工务和供电系统HUA患病率高于其他系统。该地区铁路职工血尿酸水平及高尿酸血症患病率较高,男性高于女性,年轻化趋势明显,应引起重视并加强职工的HUA与相关疾病的防治工作。

To investigate the serum uric acid (SUA) level and the epidemic characteristics of hyperuricemia (HUA) among railway workers and to provide evidence for the prevention and treatment of hyperuricemia.Physical examination data of31 415 railway workers who participated in the physical examination in a area in 2021 were collected.The prevalence characteristics of SUA and HUA were analyzed statistically.The Chi-square test was used to compare the statistical data.A ttest was used to compare the measurement data between the two groups.The results showed that the SUA level of railway workers in a region was (377.00±91.94)μmol/L,male (391.31±86.17)μmol/L,female (290.1±76.81)μmol/L.The total prevalence of HUA in the survey population was 31.43%,and that in males was 33.78%,which was higher than that in females (17.17%).The difference was statistically significant (χ^(2)=487.531,P<0.01).There was a significant difference in the prevalence of HUA among different age groups (χ^(2)=405.398,P<0.05).The prevalence rate decreased with the increase of age (trendχ^(2)=397.239,P<0.01).The incidence of HUA in males was significantly different in the age group and showed a decreasing trend with the increase of age.There were significant differences in the prevalence of HUA among different systems (χ^(2)=243.716,P<0.01).The incidence of HUA in the rolling stock,track maintenance and power supply system was higher than that in other systems.The SUA level and prevalence rate of hyperuricemia among railway workers in this area are higher,the male is higher than the female,and the trend of younger people is noticeable.Therefore,attention should be paid,and the prevention and treatment of HUA and related diseases should be strengthened.