肺水B线评分联合CA125水平、VPW对急性心力衰竭患者肺水肿的预测价值

Application Value of Pulmonary Water B-line Score Combined with CA125 Level and VPW in Pulmonary Edema in Patients with Heart Failure

【目的】探讨肺水B线评分联合糖类抗原125(CA125)水平、血管蒂宽度(VPW)对急性心力衰竭(简称急性心衰)患者肺水肿的预测价值。【方法】选择2021年2月至2022年2月本院收治的急性心衰患者100例,根据患者是否合并肺水肿分为肺水肿组(n=41)和非肺水肿组(n=59)。比较两组肺水B线评分、CA125水平、VPW,绘制受试者工作特性(ROC)曲线评估肺水B线评分、CA125水平、VPW单独及联合对急性心衰患者肺水肿的预测效能。【结果】肺水肿组肺水B线评分、CA125水平、VPW明显高于非肺水肿组(P<0.05)。肺水B线评分、CA125水平、VPW对急性心衰患者肺水肿均有一定预测效能,曲线下面积分别为0.902、0.663、0.690,敏感度分别为0.927、0.659、0.683,特异度分别为0.797、0.576、0.593;而肺水B线评分、CA125水平、VPW联合预测急性心衰患者肺水肿的曲线下面积为0.967,敏感度为0.951,特异度为0.983。【结论】肺水B线评分、CA125水平、VPW对急性心衰患者肺水肿均有一定预测效能,联合上述指标对急性心衰患者肺水肿的预测效能更高,值得临床推广应用。

【Objective】To explore the application value of pulmonary water B-line score combined with carbohydrate antigen 125(CA125)level and vascular pedicle width(VPW)in pulmonary edema in patients with acute heart failure(HF).【Methods】A total of 100 patients with acute heart failure admitted to our hospital from February 2021 to February 2022 were selected,and divided into pulmonary edema group(41 cases)and non-pulmonary edema group(59 cases)according to whether the patients were complicated with acute pulmonary edema.the lung water B-line score,CA125 level and VPW of the two groups were compared to draw the receiver operating characteristic curve(ROC)to evaluate the efficacy of the lung water B-line score,CA125 level and VPW alone and in combination to predict pulmonary edema in patients with acute heart failure.【Results】The pulmonary water B-line score,CA125 level and VPW in the pulmonary edema group were significantly higher than those in the non-pulmonary edema group(P<0.05).The lung water B-line score,CA125 and VPW have certain predictive effect on pulmonary edema in patients with acute heart failure.The area under the curve was 0.902,0.663 and 0.690 respectively,the sensitivity was 0.927,0.659 and 0.683 respectively,and the specificity was 0.797,0.576 and 0.593 respectively;The area under the curve of the above three indicators combined to predict pulmonary edema in patients with acute heart failure was 0.967,the sensitivity was 0.951,and the specificity was 0.983.【Conclusion】Pulmonary water B-line score,CA125 and VPW have certain predictive effect on pulmonary edema in patients with acute heart failure,while the combination of the above indicators has higher predictive effect on pulmonary edema in patients,which is worthy of clinical verification.