摘要
【目的】探讨CT直方图纹理参数评价肝硬化与肝硬化合并人类免疫缺陷病毒(HIV)感染患者腹部脂肪的差异。【方法】回顾性分析2010年1月至2012年1月四川省凉山彝族自治州第一人民医院确诊的单纯肝硬化患者(肝硬化组,n=44)、同期肝硬化合并HIV患者(合并组,n=33)。两组患者均进行L3平面腹部CT检查,用Image J软件测量CT图像腹部脂肪面积(TAA),同时采用直方图分析纹理参数,包括峰度(Kurt)、偏度(Skew)、费雷特直径或定方向接线径(Feret)、周长(Peri)、平均像素值(Mean)和积分灰度(IntDen)、面积百分比(AF),比较两组间各参数的差异。【结果】肝硬化组Peri、Kurt、AF均高于合并组,Feret、TAA、IntDen低于合并组,差异有统计学意义(P<0.05)。两组患者Skew、Mean比较,差异无统计学意义(P>0.05)。【结论】单纯肝硬化患者与肝硬化合并HIV患者腹部脂肪分布情况存在差异,Image J的纹理参数能够反映此种差异,可作为肝硬化和肝硬化合并HIV患者营养代谢分析的辅助指标。
【Objective】To explore the difference of CT histogram texture parameters in evaluating abdominal fat in patients with cirrhosis and cirrhosis complicated with HIV.【Methods】From January 2010 to January 2012,patients with simple cirrhosis(cirrhosis group,n=44)and patients with cirrhosis complicated with HIV(combination group,n=33)confirmed by the First People's Hospital of Liangshan Yi Autonomous Prefecture,Sichuan Province were retrospectively analyzed.Both groups of patients underwent L3 plane abdominal CT examination.The abdominal fat area(TAA)of the CT image was measured with ImageJ software.At the same time,the texture parameters were analyzed by histogram,including Kurt,Skew,Feret diameter or fixed direction wire diameter(Feret),perimeter(Peri),mean pixel value(Mean),integral gray level(IntDen),area percentage(AF),and the differences between the two groups were compared.【Results】Peri,Kurt and AF in the cirrhosis group were higher than those in the combined group,while Feret,IntDen and TAA in the cirrhosis group were lower than those in the combined group,with a statistically significant difference(P<0.05).There was no significant difference between Skew and Mean in the two groups(P>0.05).【Conclusion】There is a difference in the distribution of abdominal fat between patients with simple cirrhosis and patients with cirrhosis complicated with HIV.The texture parameters of Image J can reflect this difference,and can be used as an auxiliary index for nutritional metabolism analysis of patients with cirrhosis and cirrhosis complicated with HIV.
作者
阳宁静
熊亚维
廖佳佳
吴欢
周鹏
YANG Ning-jing;XIONG Ya-wei;LIAO Jia-jia(Sichuan Cancer Hospital,Chengdu Sichuan 610041)
出处
《医学临床研究》
CAS
2023年第2期268-271,共4页
Journal of Clinical Research