摘要
随着科学技术的快速发展,3D打印技术在个性化药物制造的应用日益成熟。与传统药物制造技术相比,3D打印技术可以轻松定制具有特定尺寸、形状及释放行为的药物,实现个性化用药。本文总结了几种常用于药物制造的3D打印技术原理,列举了3D打印技术用于药物制剂的特有优势及应用实例,并分析了全球药物3D打印行业的研究现状、发展动向,总结了目前存在的问题及挑战,为从事药物3D打印制剂的研究人员提供指导。
With the rapid advancement of science and technology,the application of 3D printing technology for personalized drug manufacturing is becoming increasingly sophisticated.Compared to traditional manufacturing technology,3D printing can easily customize preparations with specific sizes,shapes and release behaviors for personalized drug use.This review summarizes the principles of several 3D printing technologies commonly used in drug manufacturing,lists the unique advantages and application examples of 3D printing technology for pharmaceutical preparation,analyses the current research status and development trends of the global industry of drug 3D printing,and summarizes the current problems and challenges facing drug 3D printing,aiming to provide some guidance for researchers of 3D printed drugs.
作者
王珊珊
梁恩
王晓玲
梅冬
王增明
郑爱萍
WANG Shanshan;LIANG En;WANG Xiaoling;MEI Dong;WANG Zengming;ZHENG Aiping(College of Biotechnology,Tianjin University of Science and Technology,Tianjin 300457;Institute of Pharmacology and Toxicology,Academy of Military Medical Sciences,Beijing 100850;Department of Pharmacy,Beijing Children's Hospital,Capital Medical University,Beijing 100045,China)
出处
《中国药科大学学报》
CAS
CSCD
北大核心
2023年第1期15-22,共8页
Journal of China Pharmaceutical University
基金
国家自然科学基金资助项目(No.82073793)。
关键词
3D打印技术
3D打印药物
个性化用药
一体化制造
3D printing technology
3D printed drugs
personalized medicine
integrated manufacturing