青钱柳中一个新的酯苷类化合物

A new ester glycoside compound from Cyclocarya paliurus

对青钱柳[Cyclocarya paliurus(Batalin)Iljinskaja]叶的乙醇提取物正丁醇萃取部位进行化学成分研究。综合应用硅胶、MCI、ODS、Sephadex LH-20柱色谱、半制备高效液相色谱等多种色谱技术进行分离纯化,从中分离得到8个糖苷类化合物。根据理化性质及光谱数据分别鉴定为3-乙基-4-甲基戊酯-O-β-D-呋喃芹糖-(1→6)-β-D-吡喃葡萄糖苷(1)、胡桃苷E(2)、(4S)-α-松油醇-8-O-α-L-呋喃阿拉伯糖-(1→6)-β-D-吡喃葡萄糖苷(3)、(4S)-α-松油醇-8-O-β-D-呋喃芹糖-(1→6)-β-D-吡喃葡萄糖苷(4)、丁子香酚-O-β-D-呋喃芹糖-(1→6)-O-β-D-吡喃葡萄糖苷(5)、山柰酚-3-O-β-D-吡喃葡萄糖醛酸甲酯(6)、山柰酚-3-O-β-D-吡喃葡萄醛酸苷(7)、槲皮素-3-O-β-D-吡喃葡萄醛酸苷(8)。其中化合物1为新化合物,化合物2~6为首次从青钱柳属中分离得到。

Chemical constituents of n-butanol part of ethanol extract from the leaves of Cyclocarya paliurus(Batalin)Iljinskaja were studied.Eight glycosides were separated and purified by silica gel,MCI,ODS,Sephadex LH-20 column chromatography and semi-preparative high-performance liquid chromatography.Based on the physicochemical properties and spectral data,these compounds were 3-ethyl-4-methyl-pentyl ester-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside(1),juglanoside E(2),(4S)-α-terpineol-8-O-α-L-arabinofuranosyl-(1→6)-β-D-glucopyranoside(3),(4S)-α-terpineol-8-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside(4),eugenyl-O-β-Dapiofuranosyl-(1→6)-O-β-D-glucopyranoside(5),kaempferol-3-O-β-D-glucuronopyranosyl methylester(6),kaempferol-3-O-β-D-glucuronopyranoside(7),and quercetin-3-O-β-D-glucuronopyranoside(8).Among them,compound 1 was a new compound,and compounds 2-6 were isolated from the genus Cyclocarya for the first time.