摘要
Dear Editor,Pain is a common and complex clinical problem which affects 28%-50%of the general population and is responsible for large health-related costs.People with chronic pain often develop nociceptive sensitization,having mood and anxiety disorders as comorbidities.Sustained pain may alter the processing of affective information in the brain,thereby inducing anxio-depressive disorders.
基金
supported by the National Natural Foundation of China(81571326 and 81501153)
the Startup Funding of Shanghai Mental Health Center(2017-kyqd-01)
Feixiang Personnel Training Program of Shanghai Mental Health Center(2018-FX-02)
Shanghai Key Laboratory of Psychotic Disorders(13dz2260500)
Natural Science Research Projects in Anhui Universities(KJ2020A0218)
Applied Medicine Research Project of Hefei Health Committee(Hwk2020zd0016,AHWJ2021a036)
Funding of Key Research and Development Projects of Anhui Province(2022e07020002).