国外肾移植受者感染新型冠状病毒奥密克戎变异株临床特点、治疗方式及疫苗接种效果评价

Clinical characteristics,treatment and vaccination effect of SARS-CoV-2 Omicron variant infection in kidney transplant recipients abroad

新型冠状病毒(severe acute respiratory syndrome coronavirus 2,SARS-CoV-2)奥密克戎变异株(Omicron)具有极高的传染性,但相对早期的病毒分型症状较轻、预后较好。本文通过回顾性分析近年来国外关于肾移植受者(kidney transplant recipients,KTR)感染Omicron的临床特点、治疗预后以及疫苗接种效果的相关研究,从KTR感染Omicron的临床表现及与早期分型的对比、KTR与普通人群感染Omicron的临床特点比较、国外KTR感染Omicron后的治疗、疫苗接种对于KTR预防Omicron感染的效果及增加疫苗效能的措施和当前研究存在的不足几个方面,进行分析总结。

The Omicron variant of Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is highly contagious,but compared to early virus typing has milder symptoms and better prognosis.This article reviewed and analyzed the clinical characteristics,treatment,prognosis and vaccination effect of Omicron infection in Kidney transplant recipients(KTR)in recent years.The clinical manifestations of KTR infected with Omicron and the comparison with early variants,the clinical characteristics of KTR infected with Omicron compared with the general population,the treatment of KTR infected with Omicron after foreign countries,the effect of vaccination on KTR to prevent Omicron and the measures to increase the ted of vaccine,the summary of the prevention and treatment of KTR infected with Omicron abroad and the experience and the shortcomings of the current researches were analyzed and summarized.