四种抗菌药物治疗儿童急性感染性腹泻的成本-效果分析

Cost-effectiveness Analysis of Four Kinds Antibiotics for the Treatment of Acute Infectious Diarrhea in Children

目的研究四种抗菌药物治疗儿童急性感染性腹泻的成本-效果,并进行评价,以促进临床合理用药。方法回顾性查阅某医院2019年3月~2022年3月儿童急性感染性腹泻病例230例,根据不同的给药方案将病例分为四组(A组:头孢唑肟;B组:头孢噻肟;C组:头孢他啶;D组:头孢米诺),运用成本-效果法分析四种抗菌药物治疗方案的经济性。结果A、B、C、D组四组的成本分别为3547.42元,3388.24元,3082.77元,3620.74元;有效率分别为91.55%,90.77%,95.08%,90.90%;成本-效果比分别为38.75,37.33,32.42,39.83。结论头孢他啶是四种抗菌药物中治疗儿童急性感染性腹泻的最经济有效的治疗方案。

OBJECTIVE To study the Cost-effectiveness of four kinds antimicrobial agents in the treatment of acute infectious diarrhea in children and evaluate them to promote rational drug use in clinic practice.METHODS A retrospective survey was conducted in 230 cases of acute infectious diarrhea in children from March 2019 to March 2022 in a hospital.The cases were divided into 4 groups according to different therapy regimens(group A:ceftizoxime;group B:cefotaxime;group C:ceftazidime;group D:cefminox),and subjected to a cost-effectiveness analysis of the economy.RESULTS The costs of group A,B,C,D were 3547.42 yuan,3388.24 yuan,3082.77 yuan,3620.74 yuan,respectively;effective rates were 91.55%,90.77%,95.08%,90.90%,respectively;and the cost-effectiveness ratios of these groups were 38.75,37.33,32.42,39.83,respectively.CONCLUSION Of the four schemes,the treatment with Ceftazidime was the most economic for acute infectious diarrhea in children.