老年特发性膜性肾病诊治的研究进展

Research progress in the diagnosis and treatment of idiopathic membranous nephropathy in the elderly

近年来,老年肾病综合征(NS)的发病率有逐年增高的趋势。在我国,特发性膜性肾病(IMN)是老年NS最重要的病因。虽然老年IMN的临床表现与年轻人相似,但由于老年IMN患者的自身特点及其对药物治疗不良反应明显较多、疾病进展相对迅速、预后较差,因此在对其进行诊治时,我们应重视疾病的早期诊断,及时采取针对性的治疗措施。目前主要的相关治疗方式包括保守治疗、免疫治疗。

In recent years,the incidence of nephrotic syndrome(NS)in the elderly has been increasing year by year.Idiopathic membranous nephropathy(IMN)is the most important cause of NS in the aged in our country.Although the clinical manifestations of elderly patients with IMN are similar to those of young people,due to the characteristics of elderly patients with IMN and their obvious adverse reactions to drug therapy,relatively rapid disease progression,and poor prognosis,we should pay attention to the early diagnosis of the disease and timely take targeted treatment measures when diagnosing and treating them.At present,the main treatment methods include conservative therapy and immunotherapy.