两种不同条件对中药膏方制作质量的影响

Comparative study of Two Different Conditions in the Preparation of Chinese Medicine Paste

目的 通过负压与常压两种不同浓缩条件的对比,探讨中药膏方的最佳浓缩工艺。方法 以护肝利湿膏、卵巢护养膏、内异膏为研究对象,考察膏方制作过程中常压及负压条件对膏方含不溶物、有效成分含量、稳定性方面的影响,并对比不同浓缩条件的成本消耗。结果 负压浓缩耗时约为常压浓缩的50%,且没有焦屑等不溶物,得到的浓缩液有效成分含量更高;两种方法制备的成品稳定性一致,且负压浓缩的成本为常压浓缩的50%。结论 负压浓缩比常压浓缩更适合用于膏方制作。

Objective This article discussed the comparison of negative pressure and normal pressure concentration condition in order to investigate the best concentration process of Chinese medicine paste preparation. Methods The effects of atmospheric pressure and negative pressure conditions during herbal ointment manufacturing process on the insoluble matter, effective component content and stability of the finished product of herbal ointment were investigated by taking huganlishi cream, ovarian nursing cream and endometriosis cream as the research objects. The cost of two different condition of concentration was also compared in this paragraph. Result The time of negative pressure concentration is about 50% of that of atmospheric pressure concentration, and there is no insoluble substance in concentrated solution. The content of active ingredient in the concentrated solution is higher under negative pressure concentration.The stability of herbal ointment prepared by the two methods is the same, and the cost of vacuum concentration is 50% of that of atmospheric concentration. Conclusion Negative pressure concentration is more suitable for paste preparation than atmospheric pressure concentration.