Yinjia pill inhibits persistent Chlamydia trachomatis infection

To the Editor:Chlamydia trachomatis(C.trachomatis)is obligate intracellular pathogens,often resulting in development of chronic disease and tissue damage as a consequence of the host inflammatory immune response as well as persistent infections,[1]which is associated with the activation of mitogen-activated protein kinase(MAPK)and extracellular regulated protein kinases(ERK)mediated by Toll-like receptors(TLRs)and myeloid differentiation primary response gene 88(MyD88).[2]Furthermore,C.trachomatis has evolved the ability to block the apoptosis of its host cells involving the interaction of autophagy and apoptosis.[3]Novel strategies to prevent and treat C.trachomatis infection effectively are needed.