低温条件下常用环境消毒剂对新冠病毒灭活效果的CFD模拟和分析

CFD Simulation and Analysis of Inactivation Effect of Common Environmental Disinfectants on SARS-CoV-2 at Low Temperature

新冠肺炎疫情以来,冷链食品外包装上的新冠病毒频繁引起局部疫情,对现有的环境消杀体系带来了巨大挑战。为了探究低温环境消毒剂灭活效果下降的内在机制,并为冷链过程中合理选用消毒剂提供依据,对低温条件下消毒剂的灭活过程进行计算流体力学(CFD)建模。以环境消杀常用的75%乙醇溶液和次氯酸钠溶液为工作体系,探讨了不同温度下两种溶液对新冠病毒灭活特性的影响规律。结果表明,75%乙醇溶液的灭活特性在低温环境下受温度的影响较小,而次氯酸钠溶液在环境温度为253.15 K时会发生凝固现象使得其灭活效率显著降低。该模型的模拟结果与实验结果趋势一致,可为冷链运输中疫情防控提供参考。

Since the outbreak of COVID-19,SARS-CoV-2,on outer packaging of cold chain foods has frequently caused local epidemics,which has incurred a great challenge to the existing environmental disinfection system.In order to explore the internal mechanism of the decreasing inactivation effect at low temperature and provide a basis for the choice of disinfectants,a computational fluid dynamics(CFD)model of the inactivation process was established in this study.The effect laws under different temperature on the inactivation character of 75%ethanol solution and sodium hypochlorite solution was studied.The results showed that at lower temperature,it had less influence on the inactivation character of 75%ethanol solution,while the sodium hypochlorite solution would coagulate at 253.15 K,which significantly decreased its inactivation efficiency.The simulation results are accorded with the drift of experimental results,which could provide a certain theoretical basis for epidemic prevention and control in the cold chain transportation.