儿童口腔扁平苔藓的疾病特征及管理模式

Disease Characteristics and Management Model of Oral Lichen Planus in Children

口腔扁平苔藓是一种常见的口腔黏膜慢性炎性疾病,好发于中年女性,儿童较罕见。尽管尚无癌变报道,但部分儿童口腔扁平苔藓病例可出现糜烂、疼痛等症状,且易复发、迁延不愈,给患儿身心健康造成危害。本文通过回顾1991~2021三十年间的中英文文献,分析总结了儿童口腔扁平苔藓在流行病学、病因、临床表现、组织病理学、诊断、治疗、预后等各方面的疾病特征,并首次提出和三级预防模式相呼应的儿童口腔扁平苔藓疾病管理模式,以期为儿童口腔扁平苔藓的规范化诊疗和管理提供有益参考。

Oral lichen planus(OLP)is a common chronic inflammatory oral mucosal disease,which is frequently encountered in middle-aged females but rarely in children.Showing erosion,pain,and even high rates of recurrent and recalcitrant,some cases of OLP in children(OLPc)have a significant physical and psychological impact on children,although there is no report about its malignant transformation so far.This study reviewed relevant domestic and foreign literature published between 1991 and 2021,to summarize the disease characteristics of OLPc including epidemiology,etiology,clinical manifestations,histopathology,diagnosis,treatment,prognosis,et al.Besides,we proposed a disease management model of OLPc corresponded with the tertiary prevention strategies for the first time,which might have a beneficial reference to the standardized diagnosis,treatment,and management of OLPc.