振动排痰对AECOPD患者炎症因子及生活质量的影响

Influence of Vibration Sputum Excretion on Inflammation Factors and Life Quality of Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

目的:探究振动排痰对慢性阻塞性肺疾病急性加重期(AECOPD)患者炎症因子及生活质量的影响。方法:将2021年7月-2022年5月福建中医药大学附属第二人民医院收治的100例AECOPD患者,根据随机数字表法将其分为对照组与试验组,每组50例。对照组进行常规治疗及护理,试验组在对照组的基础上进行振动排痰治疗。比较两组中医症候疗效、血清炎症因子[C反应蛋白(CRP)及白介素-6(IL-6)]、慢阻肺患者自我评估测试问卷(CAT)、中医症候积分及排痰量。结果:试验组的中医症候治疗总有效率高于对照组,差异有统计学意义(P<0.05)。治疗前,两组血清炎症因子、CAT评分、中医症候积分及排痰量比较,差异均无统计学意义(P>0.05);治疗2周,试验组的血清炎症因子、中医症候积分均低于对照组,CAT评分构成优于对照组,差异均有统计学意义(P<0.05)。试验组治疗1、2、3 d的排痰量均多于对照组,差异均有统计学意义(P<0.05)。结论:振动排痰可有效控制AECOPD患者的炎症因子及改善其生活质量,在AECOPD患者中的应用价值相对较高。

Objective:To investigate the influence of vibration sputum excretion on inflammation factors and life quality of patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Method:A total of 100 patients with AECOPD in the Second People’s Hospital Affiliated to Fujian University of Traditional Chinese Medicine from July 2021 to May 2022 were selected,they were divided into control group and experimental group according to random number table method,with 50 cases in each group.The control group was treated with routine treatment and nursing,the experimental group was treated with vibration sputum excretion on the basis of the control group.The curative effect of traditional Chinese medicine syndrome,serum inflammation factors[C reactive protein(CRP)and interleukin-6(IL-6)],chronic obstructive pulmonary disease assessment test(CAT),traditional Chinese medicine syndrome scores and sputum excretion volume were compared between the two groups.Result:The total effective rate of traditional Chinese medicine syndrome treatment in the experimental group was higher than that in the control group,the difference was statistically significant(P<0.05).Before treatment,there were no significant differences in serum inflammatory factors,CAT scores,traditional Chinese medicine syndrome scores and sputum excretion volume between the two groups(P>0.05).After 2 weeks of treatment,serum inflammatory factors and traditional Chinese medicine syndrome scores in the experimental group were lower than those in the control group,and CAT score composition was better than that in the control group,the differences were statistically significant(P<0.05).The sputum excretion volume after 1,2 and 3 d of treatment in the experimental group were higher than those in the control group,the differences were statistically significant(P<0.05).Conclusion:The vibration sputum excretion can effectively control the inflammation factors and improve the life quality of patients with AECOPD,so its application value is relatively higher.