宫腔镜电切术对子宫内膜息肉患者治疗效果及子宫内膜厚度的影响

Effect of Hysteroscopic Electrotomy on Therapeutic Effect and Endometrial Thickness of Patients with Endometrial Polyps

目的:探究宫腔镜电切术对子宫内膜息肉患者治疗效果及子宫内膜厚度的影响。方法:选取2018年2月-2020年2月南通市妇幼保健院接诊的子宫内膜息肉患者106例,按照治疗方法的不同将其分为传统手术组和宫腔镜电切组,各53例。传统手术组采用传统刮宫术进行治疗,宫腔镜电切组采用宫腔镜电切术进行治疗。观察并比较两组住院时间、术中出血量、子宫内膜厚度,采用酶联免疫吸附法检测两组白细胞介素-4(IL-4)、白细胞介素-6(IL-6)、C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α),观察并比较两组治疗效果、并发症发生情况及复发情况。结果:宫腔镜电切组住院时间短于传统手术组,术中出血量少于传统手术组(P<0.05);术后,宫腔镜电切组子宫内膜厚度低于传统手术组(P<0.05);术后,宫腔镜电切组IL-4、IL-6、CRP、TNF-α水平均低于传统手术组(P<0.05);宫腔镜电切组总有效率高于传统手术组(P<0.05);宫腔镜电切组并发症发生率及复发率均低于传统手术组(P<0.05)。结论:宫腔镜电切术治疗子宫内膜息肉具有术中出血量少,治疗总有效率高,术后并发症发生率及复发率低等优点,还能调节机体血清炎症因子水平。

Objective:To explore the effect of hysteroscopic electrotomy on therapeutic effect and endometrial thickness of patients with endometrial polyps.Method:A total of 106 patients with endometrial polyps who were admitted to the Nantong Maternal and Child Health Care Hospital from February 2018 to February 2020 were selected and divided into the traditional surgery group and the hysteroscopic electrocision group according to the different treatment methods,with 53 cases in each group.The traditional surgery group was treated with traditional dilatation and curettage,and the hysteroscopic electrotomy group was treated with hysteroscopic electrotomy.The hospital stay,intraoperative bleeding volume,and endometrial thickness were observed and compared between the two groups.Enzyme-linked immunosorbent assay was used to detect interleukin-4(IL-4),interleukin-6(IL-6),C reactive protein(CRP)and tumor necrosis factor-α(TNF-α)of the two groups.The therapeutic effects,complications and recurrence were observed and compared between the two groups.Result:The hospital stay in the hysteroscopic electrocision group was shorter than that in the traditional surgery group,and the intraoperative bleeding volume was less than that in the traditional surgery group(P<0.05).After the surgery,the endometrial thickness in the hysteroscopic electrocision group was lower than that in the traditional surgery group(P<0.05).After the surgery,the levels of IL-4,IL-6,CRP and TNF-αin the hysteroscopic electrocision group were lower than those in the traditional surgery group(P<0.05).The total effective rate in the hysteroscopic electrocision group was higher than that in the traditional surgery group(P<0.05).The incidence of complications and recurrence rate in the hysteroscopic electrocision group were lower than those in the traditional surgery group(P<0.05).Conclusion:Hysteroscopic electrotomy for endometrial polyps has the advantages of less intraoperative bleeding volume,high total effective rate,low postoperative complications rate and recurrence rate,and can also regulate the level of serum inflammatory factors.