中西医结合治疗2型糖尿病的临床效果观察

Clinical effect of integrated traditional Chinese and Western medicine on type 2 diabetes mellitus

目的探析中西医结合治疗2型糖尿病的效果。方法100例2型糖尿病患者,按照随机数字表法分为对照组和观察组,每组50例。对照组行常规西医治疗,观察组行中西医结合治疗。比较两组患者治疗前后中医证候积分、血糖指标[空腹血糖(FPG)、餐后2 h血糖(2 h PG)、糖化血红蛋白(HbA1c)]以及治疗效果、不良事件发生情况。结果治疗后,两组患者口渴喜饮、多食易饥、尿频量多、口舌干燥积分均低于本组治疗前,且观察组患者口渴喜饮积分(1.14±0.11)分、多食易饥积分(1.08±0.09)分、尿频量多积分(1.21±0.11)分、口舌干燥积分(1.61±0.15)分均低于对照组的(1.67±0.16)、(1.56±0.14)、(1.73±0.90)、(2.08±0.19)分,差异具有统计学意义(P<0.05)。治疗后,两组患者FPG、2 h PG、HbA1c水平均低于本组治疗前,且观察组患者FPG(6.75±0.64)mmol/L、2 h PG(7.89±0.76)mmol/L、HbA1c(6.72±0.64)%均低于对照组的(7.82±0.76)mmol/L、(9.21±0.90)mmol/L、(8.03±0.78)%,差异具有统计学意义(P<0.05)。观察组患者治疗总有效率为98.00%,高于对照组的86.00%,差异具有统计学意义(P<0.05)。观察组患者不良事件发生率为4.00%,低于对照组的16.00%,差异具有统计学意义(P<0.05)。结论对2型糖尿病患者予以中西医结合治疗效果显著,能将患者的血糖控制在合理范围内,从而缓解其临床症状,降低不良事件发生率,建议临床推广应用。

Objective To discuss and analyze the effect of integrated traditional Chinese and Western medicine on type 2 diabetes mellitus.Methods A total of 100 patients with type 2 diabetes mellitus were divided into a control group and an observation group according to the random numerical table,with 50 cases in each group.The control group was treated with conventional Western medicine,and the observation group was treated with integrated traditional Chinese and Western medicine.Both groups were compared in terms of traditional Chinese medicine syndrome score,blood glucose indexes[fasting plasma glucose(FPG),2 h postprandial glucose(2 h PG),glycosylated hemoglobin(HbA1c)]before and after treatment,therapeutic effect,and the occurrence of adverse events.Results After treatment,the scores of thirsty drinking,excessive food and hunger,frequent urination and dry mouth in both groups were lower than those before treatment in this group;the scores of thirsty drinking,excessive food and hunger,frequent urination and dry mouth were(1.14±0.11),(1.08±0.09),(1.21±0.11),and(1.61±0.15)points in the observation group,which were lower than(1.67±0.16),(1.56±0.14),(1.73±0.90),and(2.08±0.19)points in the control group;the differences were statistically significant(P<0.05).After treatment,the levels of FPG,2 h PG,and HbA1c in both groups were lower than those before treatment in this group;the FPG(6.75±0.64)mmol/L,2 h PG(7.89±0.76)mmol/L,and HbA1c(6.72±0.64)%in the observation group were lower than(7.82±0.76)mmol/L,(9.21±0.90)mmol/L,and(8.03±0.78)%in the control group;the differences were statistically significant(P<0.05).The total effective rate of treatment in the observation group was 98.00%,which was higher than 86.00%in the control group,and the difference was statistically significant(P<0.05).The incidence of adverse events in the observation group was 4.00%,which was lower than 16.00%in the control group,and the difference was statistically significant(P<0.05).Conclusion The integrated traditional Chinese and Western medicine has a significant effect for patients with type 2 diabetes mellitus,which can control the blood glucose of patients in a more reasonable range,so as to alleviate their clinical symptoms,reduce the occurrence of adverse events.It is recommended for clinical promotion and application.