射干抗病毒口服液薄层色谱鉴别优化研究

Optimization of TLC Identification Method for Shegan Antivirus Oral Liquid

目的 优化射干抗病毒口服液中7种药材的薄层色谱(TLC)鉴别法。方法 参照2020年版《中国药典》及相关文献,改进制剂中射干、茵陈的TLC鉴别法,增加柴胡、金银花、蒲公英、大青叶、板蓝根的TLC鉴别法。结果 TLC图主斑点清晰,分离度好,且阴性对照无干扰。结论 所建立的TLC法具有点样量少、重复性好、检测效率高等优点,可用于射干抗病毒口服液的质量控制。

ObjectiveTo optimize the thin-layer chromatography(TLC) method for the identification of seven medicinal materials in Shegan Antivirus Oral Liquid.MethodsWith reference to the Chinese Pharmacopoeia(2020 Edition)and relevant literature,the TLC identification methods of Belamcandae Rhizoma and Artemisiae Scopariae Herba in the preparation were improved,and the TLC identification methods of Bupleuri Radix,Lonicerae Japonicae Flos,Taraxaci Herba,Isatidis Folium and Isatidis Radix were established.Results established TLC methods have the advantages of small sample injection volume,good repeatability and high detection efficiency,which can be used for the quality control of Shegan Antivirus Oral Liquid.