期刊文献+

血清HBV RNA水平预测抗HBV治疗效果的研究进展 被引量:2

下载PDF
导出
摘要 在乙肝患者中,共价闭环DNA (cccDNA)持续存在于肝脏中,这是其导致慢性化的重要因素,且目前治疗药物(聚乙二醇)干扰素和核苷(酸)类似物(NA)均不能清除cccDNA。血清HBV RNA能反映共价闭合环DNA的转录活性及水平,因而其在反映治疗抗病毒方面、停药后病毒反弹预测方面有重要作用。本文综述了血清HBV RNA水平预测抗HBV治疗效果的研究进展。
出处 《肝脏》 2023年第2期261-263,共3页 Chinese Hepatology
  • 相关文献

参考文献3

二级参考文献43

  • 1Peng Hu,Jia Shang,Wenhong Zhang,Guozhong Gong,Yongguo Li,Xinyue Chen,Jianning Jiang,Qing Xie,Xiaoguang Dou,Yongtao Sun,Yufang Li,Yingxia Liu,Guozhen Liu,Dewen Mao,Xiaoling Chi,Hong Tang,Xiaoou Li,Yao Xie,Xiaoping Chen,Jiaji Jiang,Ping Zhao,Jinlin Hou,Zhiliang Gao,Huimin Fan,Jiguang Ding,Dazhi Zhang,Hong Ren.HBsAg Loss with Peg-interferon Alfa-2a in Hepatitis B Patients with Partial Response to Nucleos(t)ide Analog:New Switch Study[J].Journal of Clinical and Translational Hepatology,2018,6(1):25-34. 被引量:90
  • 2Rakhi Maiwall,Manoj Kumar.Prevention and Treatment of Recurrent Hepatitis B after Liver Transplantation[J].Journal of Clinical and Translational Hepatology,2016,4(1):54-65. 被引量:20
  • 3Lai CL,Shouval D,Lok AS,陈楠(摘译),张占卿(审校).恩替卡韦与拉米夫定治疗HBeAg阴性慢性乙型肝炎的对照研究[J].世界感染杂志,2006,6(4):396-396. 被引量:201
  • 4Kock J, Theilmann L, Galle P, et al. Hepatitis B vires nucleic acids associated with human peripheral blood mononuclear cells do not originate from replicating virus[J].Hepatology, 1996, 23(3): 405-413.
  • 5Jansen L, Kootstra NA, van Dort KA, et al. Hepatitis B virus pregenomic RNA is present in virions in plasma and is associated with a response to pegylated interferon alfa-2a and nucleos(t)ide analogues[J]. J Infect Dis, 2016, 213(2): 224-232. DOI: 10.1093/ infdis/jiv397.
  • 6Tsuge M, Murakami E, Imamura M, et al. Serum HBV RNA and HBeAg are useful markers for the safe discontinuation of nucleotide analogue treatments in chronic hepatitis B patients[J]. J Gastroenterol, 2013, 48(10): 1188-1204. DOI: 10.1007/s00535-012-0737-2.
  • 7van Bfmmel F, Barrens A, Mysickova A, et al. Serum hepatitis B virus RNA levels as an early predictor of hepatitis B envelope antigen seroconversion during treatment with polymerase inhibitors[J]. Hepatology, 2015, 61(1): 66-76. DOI: 10.1002/ hep.27381.
  • 8Wang J, Shen T, Huang X, et al. Serum hepatitis B virus RNA is encapsidated pregenome RNA that may be associated with persistence of viral infection and rebound[J]. J Hepatol, 2016 May 28. pii: S0168-8278(16)30241-0. DOI: 10.1016/j.jhep.2016.05.029.
  • 9Sung WK, Zheng H, Li S, et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma[J]. Nat Genet, 2012, 44(7): 765-769. DOI: 10.1038/ng.2295.
  • 10Jiang S, Yang Z, Li W, et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis[J]. PLoS One, 2012, 7(9): e40363. DOI: 10.1371/journal.pone.0040363.

共引文献571

同被引文献25

引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部