基于文献计量探究皮肤微生态领域相关研究热点

Research hotspots in the field of skin microecology based on bibliometrics

皮肤微生物对皮肤健康至关重要,也为皮肤治疗用药物及护肤品研发提供思路。近年来已积累了大量科研文献。文章基于Web of Science核心数据库,以“Skin microecology”,“Skin microbiome”,“Skin microbial community”,以及普遍认为和微生态失衡相关的疾病,如寻常性痤疮“Acne vulgaris”、寻常性银屑病“Psoriasis vulgaris”、特应性皮炎“Atopic dermatitis”等为关键词进行检索,同时建立排除标准,最终确定文献集合1 924篇。借助文献计量方法和知识图谱可视化软件VOSviewer,分析2010—2022年的文献情况及研究热点,由结果可以看出,近年来皮肤微生态领域研究得到全世界的持续关注,皮肤微生态失调以及皮肤微生物多样性为其主要研究热点;以中国和美国为例,分析对比其在研究领域方面的差异可知,美国主要聚焦在皮肤微生物技术手段的提升和更新,中国主要聚焦在皮肤疾病与皮肤微生态的相关性研究和治疗方案的探索。该研究旨在把握国际上皮肤微生态领域发展现状和研究重点,为我国相关研究及行业提供思路和参考。

Skin microbiome is closely related to skin health.It plays an important role in maintaining skin health,resisting the invasion of foreign microorganisms and participating in skin tissue metabolism.It also provides ideas for the research and development of skin therapeutic drugs and skin care products.In recent years,the literatures on skin microecology are increasing year by year.With the help of literature measurement method and knowledge map visualization software VOSviewer,this paper made quantitative statistics and comparative analysis on the distribution trend,distribution volume of major countries,distribution institutions and research topics from 2010 to 2022.The results show that in recent years,the research in the field of skin microecology has attracted worldwide attention.Its research topics mainly include “skin diseases caused by microecological imbalance and the relationship,pathogenesis and mechanism between some skin diseases and skin microorganisms”,“skin problems caused by harmful flora”,“diversity of skin microorganisms and influencing factors of colonization”,and “genetic correlation of skin microbial community”.The majority researches focus on the imbalance of skin microecology and the diversity of skin microorganisms.Then,the differences in research fields between China and the United States are analyzed and compared.The United States researchers mainly focus on the technical means of skin microorganisms,and the Chinese mainly focus on the research of three skin diseases.