正常高值血压人群:血压变异性和心室重塑的研究进展

People with High-Normal Blood Pressure:Blood Pressure Variability and Ventricular Remodeling

正常高值血压(也称高血压前期)是理想血压与高血压的中间阶段。早在21世纪初,人们便对其有所认识,并逐渐对其引起的靶器官损害及干预措施展开研究,但多年来各个指南中关于各阶段血压的定义、分级、治疗和干预,基本只考虑血压水平,而未考虑其波动性,这是影响血压问题深入研究及临床有效干预措施的关键问题。高血压会对心脏结构和功能造成一定的损害,而大量研究表明正常高值血压人群心脏结构和功能也出现了相应的改变,现就正常高值血压这一特殊人群的血压变异性和心室重塑做一综述。

High-normal blood pressure(also known as prehypertension)is an intermediate stage between ideal blood pressure and hypertension.As early as the beginning of the 21st century,people have known about it,and gradually studied the target organ damage and intervention measures caused by it.However,for many years,the definition,classification,treatment and intervention of blood pressure in each stage in various guidelines basically only considered the blood pressure level,without considering its volatility.It is a key problem that affects the in-depth study and effective clinical intervention measures of blood pressure.hypertension will cause damage to the structure and function of the heart,and the structure and function of the heart in people with high-normal blood pressure have also changed accordingly.This article reviews the blood pressure variability and ventricular remodeling in this special population with high-normal blood pressure.