三苯胺衍生物的合成及其基于聚集诱导发光(AIE)机理对汞离子“OFF-ON”荧光识别

Synthesis of Triphenylamine Derivative and Its Recognition for Hg2+with“OFF-ON”Fluorescence Response Based on Aggregation-Induced Emission(AIE)Mechanism

汞离子(Hg^(2+))作为一种环境污染物不能被生物降解,而且还会通过食物链积累,对人体造成损害,因此,开发简单、有效检测Hg^(2+)方法具有重要意义.通过简单的两步反应合成了新颖的三苯胺衍生物Tbia,该探针在羟乙基哌嗪乙硫磺酸(HEPES)溶液中可与Hg^(2+)发生特异性反应,释放出具有聚集诱导发光(AIE)特性的前体化合物,从而实现对Hg^(2+)荧光“OFF-ON”识别.Tbia对Hg^(2+)具有良好的选择性和灵敏度,较宽的pH适用范围,检测限仅为63 nmol/L.此外,Tbia可被制成隐形墨水有望用于防伪包装,利用负载Tbia的试纸可定性或粗定量检测Hg^(2+),Tbia还能检测真实水样中的Hg^(2+),并可对活细胞中的Hg^(2+)进行荧光成像.

As an environmental pollutant,mercury ion(Hg^(2+))cannot be biodegraded,and will accumulate through the food chain and cause damage to human body.Therefore,it is of great significance to develop a simple and effective method for detecting Hg^(2+).In this paper,a novel triphenylamine derivative Tbia was synthesized by a simple two-step reaction.Tbia can react with Hg^(2+)specifically in hydroxyethylpiperazine ethane sulfonic acid(HEPES)solution and release the precursor compound with aggregation-induced emission(AIE)properties,which realized recognition of Hg^(2+)with“off-on”response.Tbia has good selectivity and sensitivity for Hg^(2+),a wide range of pH,and the detection limit of 63 nmol/L.In addition,Tbia can be prepared into invisible ink and is expected to be used in packaging of anti-counterfeiting.The test paper loaded with Tbia can be used for qualitative or roughly quantitative detection of Hg^(2+),and Tbia can detect Hg^(2+)in real water samples as well as i mage of Hg^(2+)in living cells.