早期康复治疗对急性脑梗死患者临床及血清超敏C反应蛋白水平的影响

Impact of Early Rehabilitation Therapy on the Clinical and Serum Hypersensitivity C-reactive Protein Levels of Acute Cerebral Infarction Patients

目的:探讨早期康复治疗对急性脑梗死(ACI)患者临床及血清超敏C反应蛋白(hs-CRP)水平的影响。方法:选取2020年9月—2022年6月雷州市人民医院收治的200例ACI患者为研究对象。采用均等单盲法分为对照组和研究组,各100例。对照组给予常规治疗,研究组在此基础上开展早期康复治疗,比较两组治疗效果。结果:两组治疗前Barthel指数(BI)、Fugl-Meyer肢体运动功能(FMA)评分、改良Ashworth分级(MAS)评分、改良Rankin(mRS)评分、美国国立卫生研究院卒中量表(NIHSS)评分、生活质量评分比较差异无统计学意义(P>0.05);治疗后,研究组BI、FMA评分和生活质量均高于对照组,MAS评分、mRS分级和NIHSS评分均低于对照组,差异有统计学意义(P<0.05)。两组治疗前hs-CRP水平比较差异无统计学意义(P>0.05);治疗后,研究组hs-CRP水平低于对照组,差异有统计学意义(P<0.05)。结论:ACI患者开展早期康复治疗有利于肢体功能和肌力的恢复,改善患者神经功能缺损情况,降低hs-CRP水平,减轻患者残疾程度,提高其日常生活能力与生活质量,临床治疗效果显著。

Objective:To discuss the impact of early rehabilitation therapy on the clinical and serum hypersensitivity C-reactive protein(hs-CRP)levels of acute cerebral infarction(ACI)patients.Method:A total of 200 ACI patients admitted to Leizhou City People’s Hospital from September 2020 to June 2022 were selected and divided into control group and study group according to equal single blind method,100 cases in each group.The control group was given conventional treatment,and the study group was given early rehabilitation treatment on this basis,and the therapeutic effect of the two groups was compared.Result:Before therapy,there were no significant differences between the two groups in Barthel index(BI),Fugl-Meyer assessment(FMA),modified Ashworth scale(MAS),modified Rankin scale(mRS),National Institute of Health stroke scale(NIHSS)and life quality scores(P>0.05);after treatment,BI,FMA score and quality of life in the study group were higher than those in the control group,while MAS score,mRS score and NIHSS score were lower than those in the control group,the differences were statistically significant(P<0.05).There was no significant difference in the level of hs-CRP between the two groups before treatment(P>0.05);after treatment,the level of hs-CRP in the study group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion:Early rehabilitation therapy for ACI patients is beneficial to the recovery of limb function and muscle strength,the improvement of neurological impairment,the reduction of hs-CRP level,the reduction of disability,and the improvement of their daily living ability and quality of life.The clinical therapeutic effect is remarkable.