菌酶协同异步发酵中草药对断奶仔猪生长、腹泻、免疫和抗氧化性能的影响

Effects of bacteria-enzymes synergistic asynchronous fermentation of Chinese herbal medicine on growth,diarrhea,immunity and antioxidant of weaned piglets

以3种加工处理的中草药饲喂断奶仔猪,研究其对断奶仔猪生长、腹泻、免疫、血清脂与酶及抗氧化等指标的影响。120头28±2日龄杜长大断奶仔猪分4组,3组中草药处理组饲粮分别含2%粉碎复方中草药、2%复方中草药提取液和2%发酵复方中草药,对照组饲粮不含中草药,试验期为28 d。结果表明,与对照组相比,粉碎中草药组断奶仔猪料质量比(F/G)、总蛋白(TP)含量、球蛋白(GLB)含量、总抗氧化能力(T-AOC)和超氧化物歧化酶(SOD)含量均有显著差异(P<0.05);中草药提取液组平均日增质量(ADG)、F/G、试验全期腹泻指数、免疫球蛋白G(IgG)含量、白蛋白(ALB)含量、GLB含量、TP含量、谷丙转氨酶(ALT)含量、谷草转氨酶(AST)含量、碱性磷酸酶(ALP)含量、谷胱甘肽过氧化物酶(GSH-PX)含量、总抗氧化能力(T-AOC)、SOD含量和丙二醛(MDA)含量均有显著差异(P<0.05);发酵中草药组ADG、平均日采食量(ADFI)、F/G、腹泻指数、血清IgG含量、免疫球蛋白A(IgA)含量、免疫球蛋白M(IgM)含量、ALB含量、GLB含量、TP含量、总胆固醇(TC)含量、甘油三酯(TG)含量、ALT含量、AST含量、ALP含量、GSH-PX含量、过氧化氢酶(CAT)含量、T-AOC、SOD含量和MDA含量均有显著变化(P<0.05)。由此可见,与对照组及粉碎中草药组、中草药提取液组相比,发酵中草药组中草药经菌酶协同先好氧后厌氧异步发酵能较好地改善断奶仔猪生长性能,具有抗腹泻、增强机体免疫和抗氧化功能,提示与中草药功效增强和发酵代谢产物作用叠加有关。

The effects of three processed Chinese herbal medicines on growth,diarrhea,immunity,serum lipids and enzymes and antioxidant of weaned piglets were studied.One hundred and twenty Duroc-Landrace-Yorkshire weaned piglets at 28±2 days of age were divided into four groups.The control group was fed with no Chinese herbal medicine,and the crushed Chinese herbal medicine group,Chinese herbal extract group and fermented Chinese herbal medicine group were fed with 2%crushed Chinese herbal medicine,2%compound Chinese herbal medicine extract and 2%fermented Chinese herbal medicine,respectively.The experiment lasted for 28 days.Compared with the control group,the crushed Chinese herbal medicine group was significantly different in the ratio of feed and gain(F/G),total protein(TP)content,globulin(GLB)content,total antioxidant capacity(T-AOC)and superoxide dismutase(SOD)content(P<0.05),the Chinese herbal medicine extract group was significantly different in average daily gain(ADG),F/G,diarrhea index,immunoglobulin G(IgG)content,albumin(ALB)content,GLB content,TP content,alanine aminotransferase(ALT)content,aspartate aminotransferase(AST)content,alkaline phosphatase(ALP)content,glutathione peroxidase(GSH-PX)content,T-AOC,SOD content and malonaldehyde(MDA)content(P<0.05),and the fermented Chinese herbal medicine group was significantly different in ADG,average daily feed intake(ADFI),F/G,diarrhea index,IgG content,immunoglobulin A(IgA)content,immunoglobulin M(IgM)content,ALB content,GLB content,TP content,total cholesterol(TC)content,triglyceride(TG)content,ALT content,AST content,ALP content,GSH-PX content,catalase(CAT)content,T-AOC,SOD content and MDA content(P<0.05).Compared with the control group,crushed Chinese herbal medicine group and Chinese herbal medicine extract group,the fermented Chinese herbal medicine group can improve the growth performance of weaned piglets,enhance immune and antioxidant functions,and has anti-diarrhea by aerobic and anaerobic asynchronous fermentation with bacteria and enzymes,suggesting that it is related to the superposition between the enhanced effect of Chinese herbal medicine and fermentation metabolites.