MRI脂肪抑制液体衰减反转恢复成像在滑膜炎诊断及分级中的应用

Application of MRI Fat Suppression Liquid Attenuation Inversion Recovery Imaging in the Diagnosis and Grading of Synovitis

目的探究磁共振成像(MRI)脂肪抑制液体衰减反转恢复成像(FLAIR-FS)在滑膜炎诊断和分级中的应用。方法选取109例于2020年3月至2021年7月在我院治疗的滑膜炎患者,收集患者临床资料。通过FLAIR-FS对滑膜炎患者进行诊断和分级,并与脂肪抑制质子密度加权成像(PDWI-FS)进行比较,分析检测结果的差异。对患者各观察部位滑膜厚度评级、病理评分以及病理指标评分进行比较,分析滑膜厚度评级与病理评分、病理指标、膝关节疼痛以及功能评分的相关性。结果研究组与对照组相比,两组受试者.年龄、性别以及膝关节的差异均无统计学意义(P>0.05);研究组患者的滑膜厚度显著高于对照组(P<005)。FLAIR-FS以2~3分为主,.PDWI-FS以1~2分为主,二者评分的差异显.著(P<005)。1级与2级的滑膜厚度无显著差异(P.>005);1、2级与3级的滑膜厚度的差异显著(P<005)。各观察部位滑膜厚度评级、.病理评分以及滑膜病理指标评分均无显著差异(P>005)。Pearson线性相关性分析发现,滑膜厚度评.级与病理评分、滑膜病理指标评分均呈正相关(P<0.05),与膝关节疼痛以及功能评分均无相关性(P>005)。结论滑膜炎患者的滑膜厚度有明显增高。MRI的FLAIR-FS序列对膝关节滑膜炎患者的诊断以及分级具有显著优势,可作为临床上滑膜炎的诊断工具,临床应用价值较高。且滑膜厚度评级与病理评分、滑膜病理指标评分均呈正相关,与膝关节疼痛以及功能评分均无相关性。表明MRI可用于检查滑膜炎患者的治疗疗效,但不能用主观评分来评估患者的病情。

Objective To explore the application of magnetic resonance imaging(MRI)fat suppression fluid attenuation inversion recovery imaging(FLAIR-FS)in the diagnosis and grading of synovitis.Methods 109 patients with synovitis who were treated in our hospital from March 2020 to July 2021 were selected,and clinical data of the patients were collected.FLAIR-FS was used to diagnose and classify patients with synovitis,and compared with fat-suppressed proton density-weighted imaging(PDWIFS)to analyze the differences in test results.The synovial thickness rating,pathological score and pathological index score of each observation site of the patients were compared,and the correlation between the synovial thickness rating and pathological score,pathological index,knee joint pain and functional score was analyzed.Results Compared with the control group,the differences in age,gender and knee joints of the two groups were not statistically significant(P>0.05);The thickness of the synovial membrane of the study group was significantly higher than that of the control group(P<0.05).FLAIR-FS was divided into 2~3 main,PDWI-FS was divided into main 1~2,the difference between the two scores was significant(P<0.05).There was no significant in synovial thickness between grade 1 and grade 2(P>0.05);The difference in synovial thickness between Grade 1,2 and Grade 3 was significant(P<0.05).There were no statistically significant differences in the synovial thickness rating,pathological score,and synovial pathological index score of each observation site(P>0.05).Pearson linear correlation analysis found that the synovial thickness rating was positively correlated with pathological scores and synovial pathological index scores(P<0.05),and there was no correlation with knee joint pain and functional scores(P>0.05).Conclusion The thickness of the synovial membrane in patients with synovitis is significantly increased.The FLAIR-FS sequence of MRI has significant advantages in the diagnosis and classification of patients with knee synovitis,and it can be used as a clinical diagnostic tool for synovitis and has high clinical application value.Moreover,the synovial thickness rating is positively correlated with pathological scores and synovial pathological index scores,but there is no correlation with knee joint pain and functional scores.It shows that MRI can be used to check the therapeutic effect of patients with synovitis,but the subjective score cannot be used to evaluate the patient's condition.