同型半胱氨酸、脂蛋白a、尿酸单独对冠心病患者冠状动脉狭窄程度的检测分析

Detection and Analysis of the Degree of Coronary Artery Stenosis in Patients with Coronary Heart Disease by Homocysteine,Lipoprotein A and Uric Acid Alone

目的分析同型半胱氨酸、脂蛋白a与尿酸分别对冠心病患者冠状动脉狭窄程度的影响。方法自本院诊治的冠心病患者中选取104例,轻度、中度与重度冠状动脉狭窄患者各有31例、40例、33例。取同期100例非冠心病患者为对照组。对比患者间的同型半胱氨酸、脂蛋白a与尿酸的水平差异与阳性率,分析冠心病患者同型半胱氨酸、脂蛋白a与尿酸间的相关性。结果不同程度冠状动脉狭窄患者与非冠心病患者在同型半胱氨酸、脂蛋白a与尿酸的阳性率上均存在明显差异,冠心病组患者的同型半胱氨酸、脂蛋白a与尿酸水平均高于对照组,重度、中度与轻度冠状动脉狭窄患者间的同型半胱氨酸、脂蛋白a与尿酸水平均存在显著差异,冠心病患者的同型半胱氨酸、脂蛋白a与尿酸相互呈正相关(P<0.05)。结论同型半胱氨酸、脂蛋白a与尿酸水平均与冠心病患者的冠状动脉狭窄程度呈正相关,有利于提升冠心病的检测阳性率,且能准确评估患者病情。

Objective To analyze the effects of homocysteine,lipoprotein A and uric acid on the degree of coronary artery stenosis in patients with coronary heart disease.Methods 104 cases of coronary artery disease were selected from our hospital,31 cases of mild,40 cases of moderate and 33 cases of severe coronary artery stenosis.A total of 100 patients without coronary heart disease were selected as the control group.The differences and positive rates of homocysteine,lipoprotein A and uric acid among patients were compared to analyze the correlation between homocysteine,lipoprotein A and uric acid in patients with coronary heart disease.Results Different degrees of coronary artery stenosis patients with coronary heart disease patients in homocysteine,lipoprotein a and uric acid are obvious differences in the positive rate of homocysteine in patients with CHD group,lipoprotein a and uric acid levels were higher than control group,patients with severe,moderate and mild coronary artery stenosis between homocysteine and lipoprotein a and uric acid levels were significantly different,There was a positive correlation between homocysteine,lipoprotein A and uric acid in patients with CHD(P<0.05).Conclusion The levels of homocysteine,lipoprotein A and uric acid are positively correlated with the degree of coronary artery stenosis in patients with CORONARY heart disease,which is beneficial to improve the detection positive rate of coronary heart disease and improve the accuracy of patients'disease assessment.