幽门螺杆菌感染相关性胃炎临床及胃镜特点200例分析

Clinical and Gastroscopic Characteristics of Helicobacter Pylori infection Associated Gastritis:Analysis of 200 Cases

目的讨论幽门螺杆菌(Hp)感染相关性胃炎临床及胃镜特点。方法抽取2019年1月至12月我院收治的200例60岁以下胃炎患者的临床资料、Hp检测结果及胃镜检查时所取得的胃粘膜组织病理资料进行回顾性分析。结果Hp感染相关性胃炎71例,检出率为35.50%,Hp感染率男女性别无差异(P>0.05),但患者各组年龄之间差异较为显著(P<0.05)。Hp感染相关性胃炎患者与非Hp感染相关性胃炎患者有腹痛例、恶心呕吐例、消化道出血例、食欲不振症状者占比比较无统计学差异(P>0.05)。与非Hp感染相关性胃炎患者相比,Hp感染相关性胃炎患者胃镜下胃粘膜有红白相间白相为主粗糙不平颗粒样变、红白相间白相为主隆起糜烂及红白相间白相为主扁平隆起表现者占比显著高(P<0.05),二者膜变薄血管透见表现比较无统计学差异(P>0.05)。结论Hp感染相关性胃炎与性别无关,年龄越高风险越大,但其临床表现缺乏特异性,胃镜下胃粘膜病理改变有一定特征,可为临床诊治提供依据。

Objective To discuss the clinical and gastroscopic characteristics of Helicobacter pylori(Hp)infection associated gastritis.Methods The clinical data,Hp test results and gastric mucosa pathological data collected during gastroscopy of 200 gastritis patients under 60 years old who were admitted and treated in the hospital during the period from January to December 2019 were collected for retrospective analysis.Results There were 71 cases of Hp infection associated gastritis,with a detection rate of 35.50%.There was no difference in the Hp infection rate between males and females(P>0.05),but there were significant differences between different age groups(P<0.05).There were no statistically significant differences in the proportions of patients with abdominal pain,nausea and vomiting,gastrointestinal bleeding and loss of appetite symptoms between patients with Hp infection associated gastritis and those with non-Hp infection associated gastritis(P>0.05).Patients with white-dominated redand-white rough granular changes,protuberant erosion and flat bulge were significantly more in the Hp infection associated gastritis group than in the non-Hp infection associated gastritis group(P<0.05).There was no statistically significant difference between the two groups in thin film and vascular permeability performance(P>0.05).Conclusion There is no correlation between Hp infection associated gastritis and gender.The higher the age,the higher the risk.Though clinical manifestations are not specific,pathological changes of gastric mucosa under gastroscopy have certain characteristics,which can provide a basis for clinical diagnosis and treatment.