麦粒灸联合康复功能训练对退行性膝关节炎患者关节疼痛的作用

Effect of wheat grain moxibustion combined with rehabilitation function training on relieving joint pain in patients with degenerative knee arthritis

目的 分析麦粒灸联合康复功能训练对退行性膝关节炎的作用。方法 选取河南省直第三人民医院于2019年3月—2022年3月收治的退行性膝关节炎患者110例,采用随机数字表法分为对照组和观察组,各55例,对照组患者在常规治疗基础上给予康复功能训练,观察组在对照组基础上给予麦粒灸治疗,比较2组临床疗效。结果 与对照组比较,观察组VAS评分[(3.51±1.62)分vs.(1.76±0.54)分]、肿瘤坏死因子-α[(29.25±3.17)ng/L vs.(23.75±2.86)ng/L]、白细胞介素6[(25.36±2.14)ng/L vs.(17.56±1.57)ng/L]、基质金属蛋白酶-1[(0.75±0.24)ng/L vs.(0.59±0.18)ng/L]、组织蛋白酶D[(153.25±28.34)pg/mL vs.(128.32±21.04)pg/mL]、基质金属蛋白酶-9[(15.24±2.54)mg/L vs.(11.05±2.17)mg/L]、基质金属蛋白酶组织抑制因子-1[(1.82±0.28)pg/mL vs.(1.54±0.16)pg/mL]水平低。观察组Lysholm膝关节评分表评分[(74.36±7.54)分vs.(82.24±8.25)分]、白细胞介素10[(27.82±5.21)ng/L vs.(34.24±6.05)ng/L]和总有效率高于对照组(均P<0.05)。结论 麦粒灸联合康复功能训练治疗退行性膝关节炎疗效显著。

Objective To analyze the effect of wheat grain moxibustion combined with rehabilitation function training on patients with degenerative knee arthritis.Methods A total of 110 patients of degenerative knee arthritis treated in the Third People’s Hospital of Henan Province from March 2019 to March 2022 were selected as the research object.They were randomly divided into control group and observation group by random number table method,with 55 cases in each group.The control group was given rehabilitation training on the basis of routine treatment,and the observation group was given wheat grain moxibustion on the basis of the control group.The clinical efficacy was compared between the two groups.Results The visual analogue scale(VAS) score [(3.51±1.62) points vs.(1.76±0.54) points],tumor necrosis factor-α[(29.25±3.17) ng/L vs.(23.75±2.86) ng/L],interleukin-6 [(25.36±2.14) ng/L vs.(17.56±1.57) ng/L],matrix metalloproteinase-1 [(0.75±0.24)ng/L vs.(0.59±0.18)ng/L],cathepsin D[(153.25±28.34) pg/mL vs.(128.32±21.04) pg/mL],matrix metalloproteinase-9 [(15.24±2.54) mg/L vs.(11.05±2.17) mg/L] and matrix metalloproteinase tissue inhibitor-1 [(1.82±0.28) pg/mL vs.(1.54±0.16) pg/mL] in the observation group were lower than those in the control group,and Lysholm knee score [(74.36±7.54) points vs.(82.24±8.25) points],interleukin-10 [(27.82±5.21) ng/L vs.(34.24±6.05) ng/L] and clinical efficacy were higher than those in the control group(P<0.05).Conclusion Wheat grain moxibustion combined with rehabilitation function training in the treatment of degenerative knee arthritis has a significant effect.