术前应用昂丹司琼和地佐辛对无痛负压吸宫术舒适度的影响

Effects of ondansetron and dezocine before painless abortion with suction evacuation of women on their comfort

目的:探讨术前应用昂丹司琼和地佐辛对无痛负压吸宫术受术者舒适度的影响。方法:2022年3月对200例ASA I~II级无痛负压吸宫术者进行术后舒适度调查(对照组),2022年4月入选200例ASA I~II级无痛负压吸宫术受术者(观察组),于术前5min给予地佐辛注射液5mg和昂丹司琼注射液4mg入壶。两组均静脉缓慢推注丙泊酚2mg/kg和瑞芬太尼2μg/kg进行全身麻醉的诱导和维持。比较两组消毒阴道时是否舒适、术后恶心呕吐和腹痛情况,及手术时间,手术结束至苏醒时间,离室时间。结果:观察组阴道消毒时不适感发生率由90%降至为0;术后中重度腹痛发生率由56.5%降至4.5%,VAS评分由(6.3±1.8)分降至(2.8±1.8)分;术后恶心呕吐发生率由36.5%降至5.5%;观察组苏醒时间和离室时间未发生延迟(P>0.05)。结论:无痛负压吸宫术前应用昂丹司琼和地佐辛可以提高受术者的舒适度。

Objective:To discuss the effects of ondansetron and dezocine before painless abortion with suction evacuation of women on their comfort.Methods:A postoperative comfort survey was conducted in the women after ASA Ⅰ-Ⅱ painless abortion with suction evacuation.200 women in March 2022 were selected in control group,and 200 women in April 2022 were selected in study group.The women in the two groups were given propofol 2mg/kg and remifentanil 2μg/kg injected intravenously to induce and maintain anesthesia during general anesthesia.And the women in the study group were given intravenous injection of 5mg dezocine and 4mg ondansetron 5min before abortion additionally.The situation of comfort during vaginal disinfection,the situations of postoperative nausea and vomiting,and abdominal pain,the operation time,the time from the end of the abortion to awakening,and the time of leaving the operative room of the women were compared between the two groups.Results:Compared those of the women in the control group,those the women in the study group,the incidence of discomfort of the women in the study group during vaginal disinfection had decreased from 90%to 0,the incidence of moderate and severe postoperative abdominal pain of the women in the study group had decreased from 56.5%to 4.5%,the VAS score of the women in the study group had decreased from 6.3±1.8 points to 2.8±1.8 points,and the incidence of postoperative nausea and vomiting of the women in the study group had decreased from 36.5%to 5.5%,but the awakening time and the time of leaving the operative room of the women in the study group hadn't delayed(P>0.05).Conclusion:The application of ondansetron and dezocine before painless abortion with suction evacuation of the women can improve their comfort.