胚胎移植术中18G或17G取卵针的取卵效果及手术相关指标比较

Efficacy of 18G or 17G ovum extraction needle used during in vitro ferillization-embryo transfer of patients and their correlative indexes comparison

目的:探讨体外受精-胚胎移植(IVF-ET)技术中18G或17G取卵针的应用效果及对手术相关指标影响。方法:分析2017年10月-2021年6月本院收治的125例经阴道B超引导下行取卵术的患者临床资料,术前均自行阴道冲洗,根据辅助生殖技术时取卵针直径的不同分为18G取卵针60例(18G组)或17G取卵针65例(17G组),比较两组取卵相关指标差异。结果:两组取卵相关指标无差异(P>0.05);18G组术后并发症总发生率(13.3%)、感染发生率(5.0%)均低于17G组(29.2%、16.9%)(P<0.05);两组术后卵巢储备功能相关性激素水平无差异(P>0.05);18G组疼痛评分(2.0±0.5分)低于17G组(2.8±0.9分),患者满意度(91.6%)高于17G组(75.4%)(P<0.05);两组妊娠结局比较无差异(P>0.05)。结论:不孕症患者自行阴道冲洗基础上应用更细直径的取卵针的取卵效果、卵巢储备功能及妊娠结局并无明显差异,但可降低患者取卵相关并发症、感染及疼痛感,提高患者满意度。

Objective:To investigate the efficacy of 18G or 17G egg ovum extraction needle used during in vitro fertili-zation-embryo transfer(IVF-ET)of patients,and to study the differences of their surgery related indicators.Methods:A total of 125 patients admitted to the affiliated hospital of Nantong university from October 2017 to June 2021 who underwent oocyte extraction by the guidance of transvaginal B-ultrasound were analyzed.All the patients had self-vaginal irrigation before surgery.These patients were divided into group A(60 cases with 18G ovum extraction needle used)and group B(65 cases with 17G ovum extraction needle used)according to the diameter of the ovum extraction needle in assisted reproductive technology.The differences of related indexes of egg ovum extraction of the patients were compared between the two groups.Results:There was no significant difference in the related indexes of egg ovum extraction of the patients between the two groups(P>0.05).The incidences of postoperative complications(13.3%)and infection(5.0%)of the patients in group A were significantly lower than those(29.2%and 16.9%)of the patients in group B(P<0.05).There were no significant differences in the levels of the sex hormones related to ovarian reserve function of the patients between the two groups(P>0.05).The pain score(2.00.5 points)of the patients in group A was significantly lower than that(2.8±0.9 points)of the patients in group B,and the satisfaction rate(91.6%)of the patients in group A was significantly higher than that(75.4%)of the patients in group B(P<0.05).There was no significant difference in the pregnancy outcomes of the patients between the two groups(P>0.05).Conclusion:Based on the self-vaginal irigation before surgery,the effect of ovum extraction,the ovarian reserve function,and the pregnancy outcomes of the infertility patients with the finer diameter ovum extraction needle used during IVF-ET have no significantly changes,but which can significantly reduce the complications,the infection rate,and the pain of the related ovum extraction,and can improve the satisfaction of the patients.