细胞外囊泡在肺炎中作用机制及其诊疗研究

Study on the Mechanism of Extracellular Vesicles in Pneumonia and its Diagnosis and Treatment

重症肺炎起病急、进展快、病死率高,是临床常见的呼吸系统急重症疾病。细胞外囊泡是细胞释放出去的一种异质性囊泡,细胞外囊泡作为细胞间通信的重要信息介质,直接影响受体细胞的多种生物行为。最新研究表明,细胞外囊泡和肺炎的发展有密切关系,特别是细胞外囊泡在肺炎中的诊断应用及治疗效果取得明显进展。本文综述了细胞外囊泡在肺炎中诊断和治疗作用的研究进展。

Severe pneumonia is a common respiratory acute and severe disease with acute onset,rapid progression and high mortality.Extracellular vesicles are heterogeneous vesicles released by cells.As an important information medium for intercellular communication,extracellular vesicles directly affect various biological behaviors of recipient cells.Recent studies have shown that extracellular vesicles are closely related to the development of pneumonia,especially the diagnosis and treatment of extracellular vesicles in pneumonia.This article reviews the research progress of extracellular vesicles in the diagnosis and treatment of pneumonia.