期刊文献+

验方平郁方治疗帕金森病抑郁30例 被引量:3

Experiential Effective Pingyu Prescription in the Treatment of Parkinson’s Disease Depression
下载PDF
导出
摘要 目的 观察验方平郁方治疗帕金森病抑郁的临床疗效。方法 将60例帕金森病抑郁患者随机分为2组,分别给予平郁方加减、盐酸文拉法辛缓释胶囊治疗,治疗12周后对比评定疗效。结果 试验组:治愈22例,显效5例,有效2例,无效1例,不良反应0例。总有效率:96.7%(29/30),治愈率73.3%(22/30)。对照组:治愈13例,显效12例,有效2例,无效5例,不良反应16例。总有效率:83.3%(25/30),治愈率43.3%(13/30)。结论 验方平郁方治疗帕金森病抑郁疗效显著,而且治疗费用相对较低,安全性高,大部分患者能够承受,得到患者的认可。 Objective To observe the clinical effect of Pingyu prescription in the treatment of Parkinson’s disease depression.Methods Sixty patients with Parkinson’s disease depression were randomly divided into two groups,which were treated with Pingyu prescription and venlafaxine hydrochloride sustained release capsules respectively.After 12 weeks of treatment,the therapeutic effect was compared and evaluated.Results In the experimental group,22 cases were cured,5 cases were obvious effective,2 cases were effective,1 case was ineffective and 0 cases were adverse reaction,and the total effective rate and the cure rate was 96.7%(29/30) and 73.3%(22/30),respectively.In the control group,13 cases were cured,12 cases had obvious effect,2 cases were effective,5 cases were ineffective,16 cases were adverse reactions,and the total effective rate and the cure rate was 83.3%(25/30) and 43.3%(13/30).Conclusion Pingyu prescription has a significant therapeutic effect in the treatment of Parkinson’s disease depression,and the treatment cost is relatively low,has high safety,most patients can bear,and has been recognized by patients.
作者 蔺通通 卢正海 杨丽芳 徐伟娜 马春岩 LIN Tongtong;LU Zhenghai;YANG Lifang;XU Weina;MA Chunyan(Encephalopathy Department,Weifang Hospital of Traditional Chinese Medicine,Shandong Province,Weifang 261000,China)
出处 《光明中医》 2023年第4期676-678,共3页 GUANGMING JOURNAL OF CHINESE MEDICINE
基金 山东省潍坊市科技发展计划项目(No.2020YX024)。
关键词 帕金森病 抑郁 平郁方 临床观察 Parkinson’s disease depression Pingyu prescription clinical observation
  • 相关文献

参考文献2

二级参考文献21

  • 1董青,王智樱,李焰生.帕金森病合并抑郁障碍的临床研究[J].神经病学与神经康复学杂志,2009,6(3):169-172. 被引量:10
  • 2Grover S, Somaiya M, Kumar S, et al. Psychiatric aspects of Parkinson' s disease [J ]. J Neurosci Rural Pract, 2015,6 ( 1 ) : 65 -76.
  • 3Gibb WR, Lees A. The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease [J]. J Neurol Neurosurg Psychiatry, 1988,51 (6) : 745-752.
  • 4Ketharanathan T, HanweUa R, Weerasundera R, et al. Major depressive disorder in Parkinson's disease: a cross-sectional study from Sri Lanka [J]. BMC Psychiatry Psychiatry, 2014, 14 : 278-284 .
  • 5Reijnders JS, Ehrt U, Weber WE, et al. Asystematic review of prevalence studies of depression in Parkinson' s disease [J].Movement Disorders, 2008,23(2) : 183-189.
  • 6Chagas MH, Moriyama TS, Felicio AC, et al. Depression increases in patients with Parkinson's disease according to the increasing severity of the cognitive impairment [J]. Arq Neuropsiquiatr, 2014,72 (6) : 426-429.
  • 7Braak H, Ghebremedhin E, Rub U, et al. Stages in the development of Parkinson's disease related pathology [J]. Cell Tissue Res, 2004,318(1) : 121-134.
  • 8Aarsland D, Pahlhagen S, Ballard CG, et al. Depression in Parkinson disease-epidemiology, mechanisms and management [J]. Nat Rev Neurol, 2011,8(1) :35-47.
  • 9Rojo A, Aguilar M, Garolera MT, et al. Depression in Parkinson's disease: clinical correlates and outcome [J]. Parkinsonism Relat Disord , 2003,10( 1 ) : 23-28.
  • 10Poewe W, Luginger E. Depression in Parkinson's disease: impediments to recognition and treatment options [J ]. Neurology, 1999,52(7Suppl 3) :S2-6.

共引文献38

同被引文献48

引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部