摘要
CMTM2基因在雄性动物的睾丸组织中高度表达,其可以通过一系列的分子机制来影响繁殖性能,如通过调节雄激素受体在睾丸组织中的表达来影响精子发生;CMTM2的异常表达会引起睾酮分泌异常,导致睾丸萎缩,最终导致雄性不育。为此,本文首先介绍了CMTM2基因及其表达特征,综述了该基因对雄性动物生殖系统的影响以及它与雄性动物不育之间的关系,以期为动物的品种选育及繁殖率的提高提供新思路。
CMTM2 gene is highly expressed in testicular tissue of male animals, and it can affect reproductive performance through a series of molecular mechanisms, such as regulating the expression of androgen receptor in testicular tissue to affect spermatogenesis. Abnormal expression of CMTM2 can cause abnormal testosterone secretion, resulting in testicular atrophy,and ultimately male infertility. In this paper, we first introduced the CMTM2 gene and its expression characteristics, and reviewed the effect of CMTM2 gene on the reproductive system of male animals and its relationship with male sterility, in order to provide new ideas for breeding and improving the reproductive rate of animals.
作者
何礼邦
王志颖
王新雨
潘传英
郭振刚
蓝贤勇
HE Libang;WANG Zhiying;WANG Xinyu;PAN Chuanying;GUO Zhengang;LAN Xianyong(College of Animal Science and Technology,Northwest A&F University,Shaanxi Yangling 712100,China;Bijie Institute of Animal Science,Guizhou Bijie 551700,China;Guizhou Xinwumeng Ecological Animal Husbandry Development Co.LTD.,Guizhou Hezhang 553200,China)
出处
《中国畜牧杂志》
CAS
CSCD
北大核心
2023年第2期53-57,共5页
Chinese Journal of Animal Science
基金
2021年“西部之光”访问学者项目(2021)
贵州省科研机构创新能力建设专项(黔科合服企[2021]12-02)
毕节市科技计划“揭榜挂帅”项目(毕科合重大专项字[2021]2号)
大学生科创项目(X202110712015)。