摘要
舌诊是中医望诊的重要内容,随着计算机技术的不断发展,基于图像处理的舌象客观化研究在较多开展,但从微观角度对舌象形成的机制研究较少。开展舌象尤其是舌苔的形成分子机制对于推动舌象客观化研究具有重要的意义。本文系统总结了当前舌象形成机制在微生态、代谢组学、蛋白组学、基因表达谱等方向的研究现状,总结了当前研究存在的问题,并对未来的研究方向和任务提出了建议。
Tongue diagnosis is important in the inspection of traditional Chinese medicine. With the continuous development of computer technology, more researches on the objectification of tongue images based on image processing have been carried out, but there are few studies on the mechanism of tongue image formation from a microscopic perspective. It is of great significance to develop the molecular mechanism of tongue image, especially the formation of tongue coating, to promote the objectification of tongue image. This paper systematically summarizes the current research status of the tongue formation mechanism in microecology, metabolomics, proteomics, gene expression profiling, etc.,summarizes the existing problems in current research, and makes suggestions for future research directions and tasks.
作者
张冬
庞稳泰
王可仪
杨丰文
张俊华
Zhang Dong;Pang Wentai;Wang Keyi;Yang Fengwen;Zhang Junhua(Center for Evidence-Based Medicine,Tianjin University of Traditional Chinese Medicine,Tianjin 300193,China;Institute of Traditional Chinese Medicine,Tianjin University of Traditional Chinese Medicine,Tianjin 300193,China)
出处
《世界科学技术-中医药现代化》
CSCD
北大核心
2022年第11期4574-4579,共6页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
国家自然科学基金委员会青年基金项目(82205316):基于高光谱图像和深度学习的中医舌诊参数量化研究,负责人:张冬
天津市卫生健康委员会中医药重点领域科技项目(2021002):中医药防治新冠肺炎证据库建立与循证评价研究,负责人:张冬。
关键词
中医舌诊
微生态
代谢组学
蛋白组学
基因表达谱
研究进展
未来展望
TCM tongue diagnosis
Microecology
Metabolomics
Proteomics
Gene expression profile
Research progress
Future prospects