基于中医诊疗指南的冠心病知识图谱构建

Knowledge Graph Construction of Coronary Heart Disease Based on Traditional Chinese Medicine Diagnosis and Treatment Guidelines

目的:运用知识图谱技术将诊疗指南中的辨证论治过程构建为可视化的知识图谱,通过程序将输入临床表现到输出相应的中医诊断和处方用药的过程进行可视化,为中医医师直观地显示诊疗过程和数据关系,为中医药诊治冠心病的标准化和规范化提供助力,为中医药诊疗的传承和推广提供技术依托。方法:采用Neo4j联合py2neo知识图谱技术,以中华中医药学会心血管病分会发布的《冠心病稳定型心绞痛中医诊疗指南》为模式构建知识图谱,通过编程实现以临床表现的输入调用知识图谱,可视化展示冠心病稳定型心绞痛的中医规范化诊疗过程。结果:使用py2neo库调用Neo4j,从诊疗指南中提取整理好的结构化数据导入Neo4j,构建基于冠心病稳定型心绞痛中医诊疗指南的知识图谱,且该知识图谱支持图数据库查询功能。结论:该研究结合目前中医诊疗经验传承中存在的问题,针对冠心病稳定型心绞痛这个单一病种,笔者提出了一种基于凝结了中医行业专家经验和循证证据所形成的诊疗指南,实现基于中医诊疗指南和专家经验的知识图谱可视化展示过程,为直观地展现从症状输入到遣方用药的整个中医诊疗过程和辅助中医经验传承提供助力,为中医的标准化和规范化诊疗提供了一种可参考的新范式。

Objective:To construct the syndrome differentiation and treatment process in the diagnosis and treatment guideline into a visual knowledge graph using knowledge graph technology,and visualize the process from the input of clinical manifestations to the output of corresponding traditional Chinese medicine(TCM)diagnosis and prescriptions through programs,to visually display the diagnosis and treatment process as well as the data relationship for TCM practitioners.This paper facilitated the standardized and normalized TCM diagnosis and treatment of coronary heart disease,and provided technical support for the inheritance and promotion of TCM diagnosis and treatment.Method:Neo4j and py2neo were used to construct a knowledge graph based on the Guideline for Diagnosis and Treatment of Coronary Heart Disease with Stable Angina Pectoris published by China Association of Chinese Medicine Cardiovascular Disease Branch.A knowledge graph regarding the input of clinical manifestations was built through programs,visually displaying the standardized TCM diagnosis and treatment process of coronary heart disease with stable angina pectoris.Result:The structured data were extracted from the guideline by py2neo connecting to Neo4j and imported into Neo4j to construct the knowledge graph of TCM diagnosis and treatment of coronary heart disease with stable angina pectoris,which had graph database query function.Conclusion:Aiming at the problems existing in the inheritance of TCM diagnosis and treatment,this paper proposed a diagnosis and treatment guideline integrating the experience of TCM experts and evidence-based evidence for coronary heart disease with stable angina pectoris,and realized the visualization process of knowledge graph based on TCM diagnosis and treatment guideline and the experience of TCM experts.It is helpful to intuitively display the whole TCM diagnosis and treatment process from symptom input to prescriptions and inherit TCM experience,providing a new paradigm for standardized and normalized TCM diagnosis and treatment.