药学干预对喹诺酮类抗菌药物临床合理用药的价值分析

Analysis of the value of pharmacological interventions on the rational clinical use of quinolones

目的分析药学干预对喹诺酮类抗菌药物临床合理用药的价值。方法选取2018年1~12月未开展药学干预的2000张喹诺酮类抗菌药物处方作为对照组,另选取2019年1~12月开展药学干预的2000张喹诺酮类抗菌药物处方作为观察组。对比两组处方不合格情况、药物使用频率及药物利用指数。结果观察组处方不合格率9.15%低于对照组的12.90%,差异具有统计学意义(P<0.05)。对照组药物使用频率为(427.31±87.54)次、药物利用指数为(1.22±0.23);观察组药物使用频率为(287.64±42.37)次、药物利用指数为(0.87±0.18)。观察组患者的药物利用指数、药物使用频率均低于对照组,差异具有统计学意义(P<0.05)。结论喹诺酮类抗菌药物实行药学干预的效果显著,值得使用及推广。

Objective To analyze the value of pharmacological interventions on the rational clinical use of quinolones.Methods 2000 prescriptions of quinolones without pharmacological intervention from January to December 2018 were selected as the control group,and another 2000 prescriptions of quinolones with pharmacological intervention from January to December 2019 were selected as the observation group.The unqualified prescriptions,frequency of drug use and drug utilization index were compared between the two groups.Results The unqualified rate of the prescription in the observation group was 9.15%,which was lower than 12.90%in the control group,and the difference was statistically significant(P<0.05).The control group had frequency of drug use of(427.31±87.54)times,and drug utilization index of(1.22±0.23);the observation group had frequency of drug use of(287.64±42.37)times,and drug utilization index of(0.87±0.18).The drug utilization index and frequency of drug use in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).Conclusion The effect of pharmaceutical intervention of quinolones is remarkable,which is worthy of application and promotion.