基于REDCap系统建立眩晕患者专病队列研究数据库及其随访应用

Establishment of a cohort study database of vertigo patients based on REDCap system and its follow-up application

开展高质量随访对眩晕患者的临床治疗与疾病的深入研究具有重要意义。本研究介绍使用REDCap系统建立眩晕患者专病队列并长期随访的设计及使用经验。设计在线调查表单采集患者基本资料,整合眩晕头晕残障程度评估量表、平衡信心量表、匹兹堡睡眠质量量表、医院焦虑抑郁量表等作为主要研究结局收集工具,通过链接医院信息系统的方式导入患者临床检查结果。以治疗前,治疗1个月后、3个月后、6个月后、12个月后5个事件采集节点,设置和创建前述数据收集表单,梳理并制定研究质量控制流程,设置并管理不同研究者的权限,最终建立眩晕患者专病队列项目并采集随访数据。截至2022年6月22日,已收集到378名眩晕患者数据信息,并计划进一步随访。实践发现,基于REDCap建立的专病队列随访项目可实现多地点、多终端同时输入,可实现医疗数据录入、质控及权限管理,可构建随访工作日历,最终建立优质高效的研究数据库。其设计流程简单、操作容易、信息收集完整,为耳鼻喉科医师开展眩晕相关临床研究提供一个免费、便利、高效及标准化的项目管理和数据采集工具。

It is of great significance to carry out high-quality follow-ups for the clinical treatment and in-depth study of vertigo patients.This study introduces the design and experience of the REDCap system to establish a special disease cohort of vertigo patients and long-term follow-up.An online survey form was designed to collect basic data of patients,and vertigo,dizziness,and disability assessment scale,balance confidence Scale,Pittsburgh Sleep Quality Scale,Hospital Anxiety and Depression Scale were integrated as the main outcome collection tools,and clinical examination results were imported by linking to hospital information system.Five event collection nodes were used before treatment,1 month after treatment,3 months after treatment,6 months after treatment and 12 months after treatment to set and create the aforementioned data collection form,sort out and formulate the research quality control process,set and manage the authority of different researchers,and finally establish a specific disease cohort project for vertigo patients and collect follow-up data.As of 22 June 2022,data on 378 vertigo patients have been collected and further follow-up is planned.The practice found that the follow-up project of the specific disease queue established based on REDCap could realize the simultaneous input of multiple sites and multiple terminals,the realization of medical data entry,quality control and authority management,the construction of follow-up work calendar,and finally the establishment of high-quality and efficient research database.With a simple design process,easy operation,and complete information collection,it provides a free,convenient,efficient,and standardized project management and data collection tool for otolaryngologists to carry out vertigo-related clinical studies.