备孕期高血压的规范管理

Standard Management of Hypertension During the Preparation for Pregnancy

近年来由于生活压力的增加,我国越来越多的育龄期男女罹患高血压,因此如何规范管理备孕期高血压已成为当前的焦点。本文从备孕期间血压的监测与评估和降压药的使用两方面分别对育龄期男性和女性备孕期间的血压规范管理进行阐述,强调女性备孕期间的高血压管理应同时考虑母体和胎儿的安全性,选择相对安全的降压药,如甲基多巴、拉贝洛尔、硝苯地平等;男性备孕期间的高血压管理应同时考虑降压药的疗效及其对性功能和精子的影响,推荐奈必洛尔、血管紧张素转换酶抑制剂(ACEI)/血管紧张素Ⅱ受体拮抗剂(ARB)和钙离子通道阻滞剂(CCB)类药物,旨在为临床备孕期高血压的管理提供指导并为未来研究提供参考方向。

In recent years,due to the increase of life stress,there is an increasing number of the men and women of childbearing age suffering from hypertension in China.Therefore,the standardized management of hypertension during the preparation for pregnancy has become a current focus.The standardized management of blood pressure of males and females of childbearing age during pregnancy preparation was discussed in this paper in terms of both monitoring and evaluating of hypertension during the preparation for pregnancy and application of antihypertensive drugs,emphasizing that the management of hypertension during pregnancy preparation in women should consider both maternal and fetal safety,choose relatively safe antihypertensive drugs such as methyldopa,labetalol,nifedipine,etc;the management of hypertension during pregnancy preparation in men should consider the efficacy of antihypertensive drugs and the effects on sexual function and sperm,Nebivolol,ACEI/ARB and CCB drugs are recommended,in order to provide guidance for the management of hypertension during the preparation for pregnancy reference direction for future research.