可吸收泪道栓及其在干眼中的应用

Absorbable punctal plug and its application in dry eye

泪道栓是一种小型泪道植入物,是目前临床上治疗干眼的主要方式。泪道栓的使用可以使自然泪液保留在眼表,对于解决长期存在的干眼问题具有很好的疗效。泪道栓的插头结构可以机械地阻挡泪管,从而发挥保留泪液的作用,同时泪道栓材料必须具有更好的生物相容性,在达到治疗的同时不会引起小管炎或其他并发症。故而选取合适的泪道栓材料一直以来是医学研究的热点。泪道栓材料一般需要具备生物相容性好、安全、舒适等特点。目前,常见的泪道栓材料主要分为可吸收泪道栓和不可吸收泪道栓,相比于不可吸收泪道栓,可吸收泪道栓往往生物相容性好、安全、可降解。本文将对目前研究中部分可吸收泪道栓材料的使用及其在干眼中的应用进行综述。

The punctal plug is a small implant inserted into the tear ducts,which is currently the main clinical treatment for dry eye.The use of punctal plugs can maintain natural tears on the ocular surface and has a good effect on solving the long-term dry eye problem.The plug structure can mechanically block the lacrimal duct to maintain tears.The material of the puntal plug must have good biocompatibility to achieve the therapeutic effect without causing tubulitis or other complications.Therefore,the selection of a suitable punctal plug material has always been a hot spot in medical research.In general,punctal plug materials must be biocompatible,safe and comfortable.At present,common punctal plug materials are mainly divided into absorbable and non-absorbable.The absorbable punctal plugs are often biocompatible,safe and degradable compared to the non-absorbable ones.The use of absorbable punctal plug materials and their application in the dry eye were reviewed in this article.