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胰腺细胞死亡在急性胰腺炎重症演变中的再认识 被引量:1

Reconsideration of pancreatic cell death in the exacerbation of acute pancreatitis
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摘要 胰腺腺泡细胞死亡是AP早期发生的主要病理生理特点,多种细胞死亡如坏死、焦亡、坏死性凋亡,细胞内容物的释放,触发了免疫炎症反应,促使AP的重症化演变,因此腺泡细胞死亡方式是决定AP进展和预后的重要因素。本文围绕胰腺腺泡细胞死亡及其引发的炎症级联反应开展深入的探讨,旨在探索阻断病理进程的关键分子干预靶点。
作者 宋鹏丽 胡国勇 Song Pengli;Hu Guoyong(Department of Gastroenterology,Shanghai General Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai Key Laboratory of Pancreatic Disease,Shanghai 200080,China)
出处 《中华胰腺病杂志》 CAS 2023年第1期10-14,共5页 Chinese Journal of Pancreatology
基金 国家自然科学基金(82170625)。
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  • 1Xiaowei Zhang,Ping Zhang,Lin An,Ningyuan Sun,Liying Peng,Weiwei Tang,Dingyuan Ma,Jun Chen.Miltirone induces cell death in hepatocellular carcinoma cell through GSDME-dependent pyroptosis[J].Acta Pharmaceutica Sinica B,2020,10(8):1397-1413. 被引量:39
  • 2[35]Poltorak A,He X,Smirnova I,Liu MY,Van Huffel C,Du X,Birdwell D,Alejos E,Silva M,Galanos C,Freudenberg M,Ricciardi-Castagnoli P,Layton B,Beutler B.Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice:mutations in Tlr4 gene.Science 1998;282:2085-2088
  • 3[1]Tenner S,Sica G,Hughes M,Noordhoek E,Feng S,Zinner M,Banks PA.Relationship of necrosis to organ failure in severe acute pancreatitis.Gastroenterology 1997; 113:899-903
  • 4[2]Buter A,Imrie CW,Carter CR,Evans S,McKay CJ.Dynamic nature of early organ dysfunction determines outcome in acute pancreatitis.Br J Surg 2002;89:298-302
  • 5[3]Beger HG,Bittner R,Block S,Buchler M.Bacterial contamination of pancreatic necrosis.A prospective clinical study.Gastroenterology 1986;91:433-438
  • 6[4]Buchler MW,Gloor B,Muller CA,Friess H,Seiler CA,Uhl W.Acute necrotizing pancreatitis:treatment strategy according to the status of infection.Ann Surg 2000;232:619-626
  • 7[5]Runkel NS,Moody FG,Smith GS,Rodriguez LF,LaRocco MT,Miller TA.The role of the gut in the development of sepsis in acute pancreatitis.J Surg Res 1991;51:18-23
  • 8[6]Medich DS,Lee TK,Melhem MF,Rowe MI,Schraut WH,Lee KK.Pathogenesis of pancreatic sepsis.Am J Surg 1993;165:46-50,discussion 51-52
  • 9[7]Gianotti L,Munda R,Alexander JW,Tchervenkov JI,Babcock GF.Bacterial translocation:a potential source for infection in acute pancreatitis.Pancreas 1993;8:551-558
  • 10[8]Goodwin GH,Sanders C,Johns EW.A new group of chromatin-associated proteins with a high content of acidic and basic amino acids.Eur J Biochem 1973;38:14-19

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