摘要
患者,男,72岁。左下肢肿物10余年,加重1年。局部术后免疫组化:CD34阴性,CD31阴性,CD117阴性,NF阴性,Desmin阴性,SMA阴性,P53阴性,CK-Pan阴性,Ki-67大于40%,S-100阳性。结合家族史及临床表现,符合NF1型恶性外周神经鞘瘤诊断。
A 72-year-old male presented with tumor on the left lower limb for more than 10 years and aggravated for 1 year.Immunohistochemical examination after local surgery showed CD34(-),CD31(-),CD117(-),NF(-),Desmin(-),SMA(-),P53(-),CK-Pan(-),Ki-67,more than 40%,S-100(+).Combined with family hitory and clinical manifestation,the diagnosis of malignant peripheral nerve sheath tumors with neurofibromatosis type 1 was macle.
作者
祖丽胡玛尔·莫沙
布瓦杰尔·亚克亚
刘建勇
康晓静
Zulihumaer·Mosha;Buwajieer·Yakeya;LIU Jianyong;KANG Xiaojing(Department of Dermatology and Venereology,People's Hospital of Xinjiang Uygur Autonomous Region,Xinjjiang Clinical Research Center For Dermatologic Diseases,Xinjiang Key Laboratory of Dermatology Research(XJYS1707),Urumqi 830001,China)
出处
《中国麻风皮肤病杂志》
2023年第4期272-274,共3页
China Journal of Leprosy and Skin Diseases
关键词
恶性外周神经鞘瘤
1型神经纤维瘤病
malignant peripheral nerve sheath tumors
neurofibromatosis type 1
