逐水膏贴敷护理联合榄香烯注射液对肺癌恶性胸腔积液患者的效果评价

Evaluation of the effect of Zhushui plaster application and nursing combined with Elemene injection on lung cancer patients with malignant pleural effusion

目的研究逐水膏贴敷护理联合榄香烯注射液,对肺癌恶性胸腔积液患者心理状态、癌因性疲乏程度、生命质量的影响。方法本研究为临床对照试验,采用便利抽样法选取2019年4月至2021年12月收治入宁波市医疗中心李惠利医院心胸外科二血管外科的100例肺癌恶性胸腔积液患者为研究对象,按随机数字表法分成对照组和试验组,每组50例。对照组接受榄香烯注射液胸腔内灌注治疗,试验组在对照组基础上予逐水膏贴敷护理。比较2组患者在治疗前后的心理状态、癌因性疲乏程度和生命质量。结果干预前2组患者一般资料比较差异均无统计学意义(均P>0.05)。2组患者干预前心理状态、癌因性疲乏程度、生命质量比较差异均无统计学意义(均P>0.05)。干预后试验组患者焦虑情绪和抑郁情绪得分分别为(64.12±3.24)、(60.38±3.00)分,低于对照组的(66.00±3.69)、(62.10±3.30)分,差异均有统计学意义(t=2.72、2.73,均P<0.05);干预后试验组感知疲乏、情绪疲乏、认知疲乏、行为疲乏得分分别为(5.66±0.59)、(5.26±0.75)、(4.00±0.93)、(5.08±0.80)分,低于对照组的(5.98±0.74)、(5.70±1.09)、(4.42±1.07)、(5.52±1.00)分,差异均有统计学意义(t值为2.10~2.46,均P<0.05);干预后试验组生命质量各维度及总评分分别为(50.54±5.09)、(52.49±4.46)、(50.40±4.40)、(48.96±3.32)、(202.38±15.42)分,高于对照组的(47.82±6.69)、(49.40±6.28)、(47.24±4.70)、(46.56±4.13)、(191.00±15.79)分,差异均有统计学意义(t值为-3.65~-2.29,均P<0.05)。结论逐水膏贴敷护理联合榄香烯注射液不仅能有效控制肺癌恶性胸腔积液患者的消极心理状态,减轻患者的癌因性疲乏程度,还能提高患者的生命质量。

Objective To study the effect of Zhushui plaster application and nursing combined with elemene injection on the psychological state,the degree of cancer-related fatigue,and the quality of life of lung cancer patients with malignant pleural effusion.Methods According to the clinical controlled trial,a total of 100 patients with malignant pleural effusion of lung cancer admitted to the Department of Cardiothoracic SurgeryⅡand Vascular Surgery of Ningbo Medical Center Lihuili Hospital from April 2019 to December 2021 were convenient selected and divided into control group and experimental group with 50 cases in each group by random number table method.The control group received intrapleural perfusion therapy with elemene injection,and the experimental group was treated with Zhushui plaster on the basis of the control group.The psychological state,cancer-induced fatigue and quality of life of the two groups before and after treatment were compared.Results There was no significant difference in baseline data between the two groups before intervention(all P>0.05).There were no significant differences in psychological status,cancer-induced fatigue and the quality of life before intervention between the two groups(all P>0.05).After the intervention,the anxious and depressed scores of the patients in the experimental group were(64.12±3.24)and(60.38±3.00),respectively,which were lower than those in the control group,(66.00±3.69)and(62.10±3.30),and the differences were statistically significant(t=2.72,2.73,both P<0.05).The scores of perceived fatigue,emotional fatigue,cognitive fatigue and behavioral fatigue in the experimental group were(5.66±0.59),(5.26±0.75),(4.00±0.93)and(5.08±0.80),respectively,which were lower than those in the control group,(5.98±0.74),(5.70±1.09),(4.42±1.07)and(5.52±1.00),respectively,and the differences were statistically significant(t values were 2.10-2.46,all P<0.05);in addition,the dimensions and total scores of the quality of life in the experimental group were(50.54±5.09),(52.49±4.46),(50.40±4.40),(48.96±3.32)and(202.38±15.42),respectively,which were higher than those in the control group,(47.82±6.69),(49.40±6.28),(47.24±4.70),(46.56±4.13)and(191.00±15.79)respectively,and the differences were statistically significant(t values were-3.65--2.29,all P<0.05).Conclusions Zhushui plaster application and nursing combined with elemene injection can not only effectively control the negative psychological state of lung cancer patients with malignant pleural effusion and reduce the degree of cancer-related fatigue,but also improve their quality of life.